Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 104562..105093 Replicon plasmid unnamed1
Accession NZ_CP039047
Organism Piscirickettsia salmonis strain Psal-073

Toxin (Protein)


Gene name relE Uniprot ID A0A7U4YYE1
Locus tag Psal073_RS16700 Protein ID WP_027243212.1
Coordinates 104562..104849 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1L6TI86
Locus tag Psal073_RS16705 Protein ID WP_027243211.1
Coordinates 104839..105093 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Psal073_RS16665 100239..101216 + 978 WP_036771347.1 IS5 family transposase -
Psal073_RS16670 101316..101741 + 426 WP_155069794.1 hypothetical protein -
Psal073_RS16675 101839..102087 - 249 Protein_122 DDE-type integrase/transposase/recombinase -
Psal073_RS16680 102176..103153 - 978 WP_036771347.1 IS5 family transposase -
Psal073_RS16685 103235..103519 + 285 WP_155069795.1 hypothetical protein -
Psal073_RS16690 103523..103978 + 456 WP_155069796.1 hypothetical protein -
Psal073_RS16695 103998..104555 + 558 WP_155069797.1 tail assembly protein -
Psal073_RS16700 104562..104849 - 288 WP_027243212.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Psal073_RS16705 104839..105093 - 255 WP_027243211.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Psal073_RS16710 105187..106929 + 1743 WP_155069798.1 host specificity protein J -
Psal073_RS16715 106982..107956 + 975 WP_036771639.1 IS30 family transposase -
Psal073_RS16720 107993..108658 + 666 Protein_131 IS30 family transposase -
Psal073_RS16725 108696..108989 + 294 Protein_132 IS6 family transposase -
Psal073_RS16730 109035..110012 - 978 WP_036771347.1 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..208052 208052


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-55)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11063.21 Da        Isoelectric Point: 10.8855

>T123461 WP_027243212.1 NZ_CP039047:c104849-104562 [Piscirickettsia salmonis]
MTYKLQFHKEAYKEWKKLNPTTQQQFQKVLKKRLINPHIPSAVCGGDLKGCYKIKLRALGYRLIYTVKKDKVVVQVLAIG
SRNRLEAYRLAASRL

Download         Length: 288 bp

>T123461 NZ_CP039047:c104849-104562 [Piscirickettsia salmonis]
ATGACTTATAAATTACAATTTCACAAAGAAGCGTATAAAGAGTGGAAAAAACTAAATCCAACAACTCAGCAACAGTTTCA
AAAAGTTTTGAAAAAACGCTTAATTAACCCACATATCCCATCAGCAGTGTGTGGTGGTGATTTAAAAGGCTGCTATAAAA
TTAAATTAAGAGCGCTCGGTTATCGTTTAATTTATACAGTGAAAAAGGACAAAGTGGTTGTTCAAGTCTTGGCCATTGGT
TCCAGAAACCGCTTAGAAGCGTATCGTTTAGCGGCAAGTCGCCTATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9554.83 Da        Isoelectric Point: 4.3176

>AT123461 WP_027243211.1 NZ_CP039047:c105093-104839 [Piscirickettsia salmonis]
MKQLYAQQSVTITELRKSPTSVINEANGEPVVILNHNVPAAYMVPPELFEAMLDSYEDRQLEGIVKKRLHSPDRDFIDVD
VDDL

Download         Length: 255 bp

>AT123461 NZ_CP039047:c105093-104839 [Piscirickettsia salmonis]
ATGAAACAGCTCTACGCACAACAGTCGGTAACAATTACAGAACTTAGAAAAAGCCCAACCAGCGTTATCAATGAAGCCAA
CGGCGAACCGGTGGTTATTTTGAATCATAATGTTCCTGCGGCGTACATGGTGCCACCTGAACTTTTTGAAGCCATGCTCG
ACTCGTATGAAGACCGCCAACTTGAAGGCATAGTCAAAAAACGTTTACATTCTCCTGACCGTGACTTTATTGATGTCGAT
GTCGATGACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U4YYE1

Antitoxin

Source ID Structure
AlphaFold DB A0A1L6TI86

References