Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 68457..68988 Replicon plasmid unnamed1
Accession NZ_CP038919
Organism Piscirickettsia salmonis strain Psal-010b

Toxin (Protein)


Gene name relE Uniprot ID A0A7U4YYE1
Locus tag Psal010b_RS16640 Protein ID WP_027243212.1
Coordinates 68701..68988 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1L6TI86
Locus tag Psal010b_RS16635 Protein ID WP_027243211.1
Coordinates 68457..68711 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Psal010b_RS16605 64331..64675 + 345 Protein_85 DDE-type integrase/transposase/recombinase -
Psal010b_RS16610 64757..65626 - 870 WP_155066904.1 hypothetical protein -
Psal010b_RS16615 65628..66605 - 978 WP_036771347.1 IS5 family transposase -
Psal010b_RS16620 66801..66989 + 189 Protein_88 hypothetical protein -
Psal010b_RS16625 67086..68063 + 978 WP_036771347.1 IS5 family transposase -
Psal010b_RS16630 68078..68239 + 162 WP_155046636.1 hypothetical protein -
Psal010b_RS16635 68457..68711 + 255 WP_027243211.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Psal010b_RS16640 68701..68988 + 288 WP_027243212.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Psal010b_RS16645 68995..69456 - 462 Protein_93 tail assembly protein -
Psal010b_RS16650 69483..70460 - 978 WP_036771347.1 IS5 family transposase -
Psal010b_RS16655 70793..71287 - 495 Protein_95 hypothetical protein -
Psal010b_RS16660 71256..71372 - 117 Protein_96 phage minor tail protein L -
Psal010b_RS16665 71461..71673 + 213 WP_053093683.1 hypothetical protein -
Psal010b_RS16670 71831..72808 + 978 WP_036771347.1 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..176541 176541


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-55)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11063.21 Da        Isoelectric Point: 10.8855

>T123367 WP_027243212.1 NZ_CP038919:68701-68988 [Piscirickettsia salmonis]
MTYKLQFHKEAYKEWKKLNPTTQQQFQKVLKKRLINPHIPSAVCGGDLKGCYKIKLRALGYRLIYTVKKDKVVVQVLAIG
SRNRLEAYRLAASRL

Download         Length: 288 bp

>T123367 NZ_CP038919:68701-68988 [Piscirickettsia salmonis]
ATGACTTATAAATTACAATTTCACAAAGAAGCGTATAAAGAGTGGAAAAAACTAAATCCAACAACTCAGCAACAGTTTCA
AAAAGTTTTGAAAAAACGCTTAATTAACCCACATATCCCATCAGCAGTGTGTGGTGGTGATTTAAAAGGCTGCTATAAAA
TTAAATTAAGAGCGCTCGGTTATCGTTTAATTTATACAGTGAAAAAGGACAAAGTGGTTGTTCAAGTCTTGGCCATTGGT
TCCAGAAACCGCTTAGAAGCGTATCGTTTAGCGGCAAGTCGCCTATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9554.83 Da        Isoelectric Point: 4.3176

>AT123367 WP_027243211.1 NZ_CP038919:68457-68711 [Piscirickettsia salmonis]
MKQLYAQQSVTITELRKSPTSVINEANGEPVVILNHNVPAAYMVPPELFEAMLDSYEDRQLEGIVKKRLHSPDRDFIDVD
VDDL

Download         Length: 255 bp

>AT123367 NZ_CP038919:68457-68711 [Piscirickettsia salmonis]
ATGAAACAGCTCTACGCACAACAGTCGGTAACAATTACAGAACTTAGAAAAAGCCCAACCAGCGTTATCAATGAAGCCAA
CGGCGAACCGGTGGTTATTTTGAATCATAATGTTCCTGCGGCGTACATGGTGCCACCTGAACTTTTTGAAGCCATGCTCG
ACTCGTATGAAGACCGCCAACTTGAAGGCATAGTCAAAAAACGTTTACATTCTCCTGACCGTGACTTTATTGATGTCGAT
GTCGATGACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U4YYE1

Antitoxin

Source ID Structure
AlphaFold DB A0A1L6TI86

References