Detailed information of TA system TA123334

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 53975..54506
• Replicon: plasmid unnamed2
• Accession: NZ_CP038883
• Organism: Piscirickettsia salmonis strain Psal-003

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: Psal003_RS17460
• Protein ID: WP_016210662.1
• Coordinates: 53975..54262 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: Psal003_RS17465
• Protein ID: WP_016210670.1
• Coordinates: 54252..54506 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Psal003_RS17425	48976..49299	+	324	WP_032126913.1	hypothetical protein	-
Psal003_RS17430	49356..49622	+	267	WP_016211142.1	DUF4035 domain-containing protein	-
Psal003_RS17435	49626..51704	+	2079	WP_032126912.1	hypothetical protein	-
Psal003_RS17440	51697..52038	+	342	WP_016210657.1	phage tail protein	-
Psal003_RS17445	52035..52706	+	672	WP_016210666.1	phage minor tail protein L	-
Psal003_RS17450	52675..53421	+	747	WP_032126911.1	C40 family peptidase	-
Psal003_RS17455	53411..53968	+	558	WP_016210665.1	tail assembly protein	-
Psal003_RS17460	53975..54262	-	288	WP_016210662.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
Psal003_RS17465	54252..54506	-	255	WP_016210670.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
Psal003_RS17470	54600..57887	+	3288	WP_016210653.1	host specificity protein J	-
Psal003_RS17475	57887..59026	+	1140	WP_032126910.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..79943	79943

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-55)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11064.15 Da
• Isoelectric Point: 10.7358

>T123334 WP_016210662.1 NZ_CP038883:c54262-53975 [Piscirickettsia salmonis]
MTYKLQFHKEAYKEWKKLNPTTQQQFQKVLKKRLINPHIPSAVCGGDLKGCYKIKLRALGYRLIYTVKEDKVVVQVLAIG
SRNRLEAYRLAASRL

Nucleotide

• Length: 288 bp

>T123334 NZ_CP038883:c54262-53975 [Piscirickettsia salmonis]
ATGACTTATAAATTACAATTTCACAAAGAAGCGTATAAAGAGTGGAAAAAACTAAATCCAACAACTCAGCAACAGTTTCA
AAAAGTTTTGAAAAAACGCTTAATTAACCCACATATCCCATCAGCAGTGTGTGGTGGTGATTTAAAAGGCTGCTATAAAA
TTAAATTAAGAGCGCTCGGTTATCGTTTAATTTATACAGTGAAAGAGGATAAAGTGGTTGTTCAAGTCTTGGCGATTGGT
TCCAGAAACCGCTTAGAAGCGTATCGTTTAGCGGCAAGTCGCCTATAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9450.69 Da
• Isoelectric Point: 4.0808

>AT123334 WP_016210670.1 NZ_CP038883:c54506-54252 [Piscirickettsia salmonis]
MKQLYAQQSVTITELRKSPTSVINEANGEPVVILNHNAPAAYMVPPELFEAMLDSYEDRQLEGIVKKRLNSPDCDFIDVD
VDDL

Nucleotide

• Length: 255 bp

>AT123334 NZ_CP038883:c54506-54252 [Piscirickettsia salmonis]
ATGAAACAGCTCTACGCACAACAGTCGGTAACCATTACAGAACTTAGAAAAAGCCCAACCAGCGTTATTAATGAAGCCAA
CGGCGAGCCGGTGGTTATTTTGAATCATAATGCTCCTGCGGCGTACATGGTGCCACCTGAACTTTTTGAAGCCATGCTCG
ACTCGTATGAAGACCGCCAACTTGAAGGCATAGTCAAAAAACGTTTGAATTCTCCTGATTGTGACTTTATTGATGTCGAT
GTCGATGACTTATAA