Detailed information of TA system TA123314

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): virAT/YafQ(toxin)
• Location: 29601..30144
• Replicon: plasmid p2
• Accession: NZ_CP038864
• Organism: Campylobacter jejuni strain SCJK2

Toxin (Protein)

• Gene name: virT
• Uniprot ID: -
• Locus tag: E5V15_RS09905
• Protein ID: WP_053868684.1
• Coordinates: 29601..29870 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: virA
• Uniprot ID: -
• Locus tag: E5V15_RS09910
• Protein ID: WP_058914785.1
• Coordinates: 29860..30144 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E5V15_RS09880 (E5V15_09880)	26063..26305	-	243	WP_052835045.1	hypothetical protein	-
E5V15_RS09885 (E5V15_09885)	26305..26610	-	306	WP_011799398.1	hypothetical protein	-
E5V15_RS09895 (E5V15_09895)	27482..29053	+	1572	WP_043012966.1	relaxase/mobilization nuclease domain-containing protein	-
E5V15_RS09900 (E5V15_09900)	29176..29487	-	312	Protein_35	hypothetical protein	-
E5V15_RS09905 (E5V15_09905)	29601..29870	-	270	WP_053868684.1	type II toxin-antitoxin system YafQ family toxin	Toxin
E5V15_RS09910 (E5V15_09910)	29860..30144	-	285	WP_058914785.1	hypothetical protein	Antitoxin
E5V15_RS09915 (E5V15_09915)	30368..30730	-	363	WP_025443372.1	hypothetical protein	-
E5V15_RS10580	30894..31604	-	711	WP_286014896.1	hypothetical protein	-
E5V15_RS09925 (E5V15_09925)	31644..32075	-	432	WP_143726017.1	hypothetical protein	-
E5V15_RS09930 (E5V15_09930)	32062..32493	-	432	WP_143726018.1	hypothetical protein	-
E5V15_RS09940 (E5V15_09940)	33028..33246	-	219	WP_143726019.1	hypothetical protein	-
E5V15_RS09945 (E5V15_09945)	33258..33563	-	306	WP_126266738.1	hypothetical protein	-
E5V15_RS09950 (E5V15_09950)	33577..33921	-	345	WP_011117579.1	hypothetical protein	-
E5V15_RS09960 (E5V15_09960)	34369..34794	-	426	WP_052835067.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	virD4 / virB11 / virB10 / virB9 / virB8 / Cjp54 / virB4	1..36143	36143

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (3-89)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10616.28 Da
• Isoelectric Point: 9.5064

>T123314 WP_053868684.1 NZ_CP038864:c29870-29601 [Campylobacter jejuni]
MPYKITLSKKYKQKYKKANTKDRILIDEVVEKLSNDETLEEKYKDHALKGNYIGFRECHIKPDLLLVYRKNNDILELYLA
NLGNHNNIF

Nucleotide

• Length: 270 bp

>T123314 NZ_CP038864:c29870-29601 [Campylobacter jejuni]
ATGCCTTATAAAATTACATTATCTAAAAAATACAAGCAAAAATATAAAAAAGCAAACACAAAAGACAGAATATTGATTGA
TGAAGTTGTTGAAAAATTATCTAATGATGAAACATTAGAAGAAAAATACAAAGACCACGCATTAAAAGGAAATTATATTG
GTTTTAGAGAATGCCACATTAAACCTGATTTGTTATTAGTCTATCGCAAAAATAATGATATTTTAGAATTATATTTGGCT
AATTTAGGAAATCACAATAATATTTTTTAG

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 11187.70 Da
• Isoelectric Point: 9.7619

>AT123314 WP_058914785.1 NZ_CP038864:c30144-29860 [Campylobacter jejuni]
MFDYSKYENASEKQLIHALTLAEKRAEKLNSQLKENNEFFKFLQKKLKKSFNAKKTKKAEQRRPELDEAIEDYKNGNVET
YANFEEYKKAMNAL

Nucleotide

• Length: 285 bp

>AT123314 NZ_CP038864:c30144-29860 [Campylobacter jejuni]
ATGTTTGATTATTCTAAATATGAAAATGCTAGCGAAAAACAATTAATACACGCTTTGACTTTAGCAGAAAAAAGGGCGGA
GAAACTAAACTCGCAATTAAAAGAGAATAACGAATTTTTTAAATTTTTACAAAAAAAGTTAAAAAAATCTTTTAACGCCA
AAAAAACAAAAAAAGCAGAGCAAAGAAGACCTGAATTAGATGAAGCGATTGAAGATTATAAAAATGGAAATGTAGAAACC
TATGCTAATTTTGAAGAATATAAAAAGGCTATGAATGCCTTATAA