Detailed information of TA system TA123206

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 459588..460241
• Replicon: chromosome
• Accession: NZ_CP038816
• Organism: Acinetobacter nosocomialis strain KAN01

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: KAN01_RS02255
• Protein ID: WP_135924501.1
• Coordinates: 459852..460241 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: N8SCE2
• Locus tag: KAN01_RS02250
• Protein ID: WP_002049719.1
• Coordinates: 459588..459845 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KAN01_RS02230	455102..456109	+	1008	WP_002049752.1	DNA-directed RNA polymerase subunit alpha	-
KAN01_RS02235	456128..456505	+	378	WP_002049717.1	50S ribosomal protein L17	-
KAN01_RS02240	456687..458177	+	1491	WP_065286445.1	NAD(P)/FAD-dependent oxidoreductase	-
KAN01_RS02245	458226..459398	-	1173	WP_002049748.1	acyl-CoA dehydrogenase family protein	-
KAN01_RS02250	459588..459845	+	258	WP_002049719.1	succinate dehydrogenase assembly factor 2	Antitoxin
KAN01_RS02255	459852..460241	+	390	WP_135924501.1	hypothetical protein	Toxin
KAN01_RS02260	461009..462094	+	1086	WP_002049690.1	hypothetical protein	-
KAN01_RS02265	462178..462744	+	567	WP_004711824.1	rhombosortase	-
KAN01_RS02270	462932..465127	+	2196	WP_006580689.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15613.63 Da
• Isoelectric Point: 9.9118

>T123206 WP_135924501.1 NZ_CP038816:459852-460241 [Acinetobacter nosocomialis]
MDSHLNFKLKYSRFAIIFQFFIGLSLVVLFYQLLPILWWLVTVSLLFISFIFFLKRPQLAQIAHLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFEGHKTLTSVIWFDQMPLSQWKQLKTLEKFY

Nucleotide

• Length: 390 bp

>T123206 NZ_CP038816:459852-460241 [Acinetobacter nosocomialis]
TTGGACAGCCATTTGAATTTCAAACTGAAATATAGCCGTTTTGCGATTATATTTCAGTTTTTTATTGGCTTAAGTTTGGT
AGTTCTATTTTATCAACTCCTACCAATATTATGGTGGTTGGTTACGGTCAGTTTACTATTCATAAGTTTTATTTTCTTTT
TAAAGCGGCCACAGCTCGCTCAAATTGCTCATTTAGATCAAAAATTATGGTCACTTAGCTTTCATTCAGAACAAACAATT
TCTCGGGTAGAGATTTTAAAAATAATTGATTATCAGATTTTCATAGTGGTCTATTTTGAAGGGCATAAGACATTAACTTC
TGTTATTTGGTTTGATCAAATGCCTCTATCTCAGTGGAAACAACTTAAAACCTTAGAAAAATTTTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10278.71 Da
• Isoelectric Point: 4.7620

>AT123206 WP_002049719.1 NZ_CP038816:459588-459845 [Acinetobacter nosocomialis]
MSEEMTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT123206 NZ_CP038816:459588-459845 [Acinetobacter nosocomialis]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAGTTTATCGCGCACGCCGCGGTTTAAAGGAAATTGATGTCTATTT
TGACCCGTATGTGAAAAATTATTATTTAAAGGCAGATCCAGCAGAAAAAGCATTATTTGCTGAATTGGTAGAGCAGGAAG
ATCCTGATTTACTTGACTGGTTTATGGAAGTATCTGAACCGCCGCGTACAGAATTACGTGATTTTATTCATAAATTAAAG
CACTATGTTCATGGCTGA

Structures

Antitoxin

• AlphaFold DB: A0A0Q1QI86