Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YoeB-DinJ |
| Location | 1842771..1843296 | Replicon | chromosome |
| Accession | NZ_CP038803 | ||
| Organism | Treponema putidum strain OMZ 846 | ||
Toxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | E4N75_RS08825 | Protein ID | WP_255804911.1 |
| Coordinates | 1842771..1843034 (-) | Length | 88 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | E4N75_RS08830 | Protein ID | WP_255804913.1 |
| Coordinates | 1843039..1843296 (-) | Length | 86 a.a. |
Genomic Context
Location: 1841564..1841662 (99 bp)
Type: Others
Protein ID: WP_255822433.1
Type: Others
Protein ID: WP_255822433.1
Location: 1843671..1844939 (1269 bp)
Type: Others
Protein ID: WP_255822437.1
Type: Others
Protein ID: WP_255822437.1
Location: 1838359..1839228 (870 bp)
Type: Others
Protein ID: WP_255822428.1
Type: Others
Protein ID: WP_255822428.1
Location: 1839261..1839773 (513 bp)
Type: Others
Protein ID: WP_255822429.1
Type: Others
Protein ID: WP_255822429.1
Location: 1839906..1840814 (909 bp)
Type: Others
Protein ID: WP_255822430.1
Type: Others
Protein ID: WP_255822430.1
Location: 1840830..1841234 (405 bp)
Type: Others
Protein ID: WP_255822431.1
Type: Others
Protein ID: WP_255822431.1
Location: 1841234..1841473 (240 bp)
Type: Others
Protein ID: WP_255822432.1
Type: Others
Protein ID: WP_255822432.1
Location: 1841703..1842110 (408 bp)
Type: Others
Protein ID: WP_255822434.1
Type: Others
Protein ID: WP_255822434.1
Location: 1842094..1842276 (183 bp)
Type: Others
Protein ID: WP_255822435.1
Type: Others
Protein ID: WP_255822435.1
Location: 1842363..1842560 (198 bp)
Type: Others
Protein ID: WP_255822436.1
Type: Others
Protein ID: WP_255822436.1
Location: 1842771..1843034 (264 bp)
Type: Toxin
Protein ID: WP_255804911.1
Type: Toxin
Protein ID: WP_255804911.1
Location: 1843039..1843296 (258 bp)
Type: Antitoxin
Protein ID: WP_255804913.1
Type: Antitoxin
Protein ID: WP_255804913.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E4N75_RS08780 (E4N75_08730) | 1838359..1839228 | - | 870 | WP_255822428.1 | radical SAM protein | - |
| E4N75_RS08785 (E4N75_08735) | 1839261..1839773 | - | 513 | WP_255822429.1 | ClbS/DfsB family four-helix bundle protein | - |
| E4N75_RS08790 (E4N75_08740) | 1839906..1840814 | - | 909 | WP_255822430.1 | YafY family protein | - |
| E4N75_RS08795 (E4N75_08745) | 1840830..1841234 | - | 405 | WP_255822431.1 | type II toxin-antitoxin system VapC family toxin | - |
| E4N75_RS08800 (E4N75_08750) | 1841234..1841473 | - | 240 | WP_255822432.1 | DUF2281 domain-containing protein | - |
| E4N75_RS08805 (E4N75_08755) | 1841564..1841662 | + | 99 | WP_255822433.1 | type II toxin-antitoxin system YoeB family toxin | - |
| E4N75_RS08810 (E4N75_08760) | 1841703..1842110 | - | 408 | WP_255822434.1 | type II toxin-antitoxin system VapC family toxin | - |
| E4N75_RS08815 (E4N75_08765) | 1842094..1842276 | - | 183 | WP_255822435.1 | hypothetical protein | - |
| E4N75_RS08820 | 1842363..1842560 | - | 198 | WP_255822436.1 | alpha/beta hydrolase | - |
| E4N75_RS08825 (E4N75_08775) | 1842771..1843034 | - | 264 | WP_255804911.1 | Txe/YoeB family addiction module toxin | Toxin |
| E4N75_RS08830 (E4N75_08780) | 1843039..1843296 | - | 258 | WP_255804913.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| E4N75_RS08835 (E4N75_08785) | 1843671..1844939 | + | 1269 | WP_255822437.1 | OmpA family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 88 a.a. Molecular weight: 10510.08 Da Isoelectric Point: 9.4465
>T123182 WP_255804911.1 NZ_CP038803:c1843034-1842771 [Treponema putidum]
MIKAWDEDAWMDYVYWQTEDKKTLKRINMLIKDIERNGHNGLGSPEPLKENLSGFWSRRIDKKNRLVYRIVDNVIQIIQC
RTHYGEK
MIKAWDEDAWMDYVYWQTEDKKTLKRINMLIKDIERNGHNGLGSPEPLKENLSGFWSRRIDKKNRLVYRIVDNVIQIIQC
RTHYGEK
Download Length: 264 bp
>T123182 NZ_CP038803:c1843034-1842771 [Treponema putidum]
ATGATTAAAGCATGGGATGAAGATGCGTGGATGGATTATGTCTATTGGCAAACAGAAGATAAAAAAACATTAAAAAGAAT
CAATATGTTGATTAAAGATATAGAAAGAAATGGTCATAATGGCTTAGGCAGTCCTGAGCCATTAAAGGAAAATCTGTCAG
GATTCTGGAGCCGCAGGATCGATAAAAAAAATAGATTGGTTTATAGAATAGTCGATAATGTGATACAAATAATTCAGTGT
AGAACCCATTATGGTGAAAAATGA
ATGATTAAAGCATGGGATGAAGATGCGTGGATGGATTATGTCTATTGGCAAACAGAAGATAAAAAAACATTAAAAAGAAT
CAATATGTTGATTAAAGATATAGAAAGAAATGGTCATAATGGCTTAGGCAGTCCTGAGCCATTAAAGGAAAATCTGTCAG
GATTCTGGAGCCGCAGGATCGATAAAAAAAATAGATTGGTTTATAGAATAGTCGATAATGTGATACAAATAATTCAGTGT
AGAACCCATTATGGTGAAAAATGA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9880.42 Da Isoelectric Point: 9.5364
>AT123182 WP_255804913.1 NZ_CP038803:c1843296-1843039 [Treponema putidum]
MAQINVNIRMDSEVKQEAEQLFDSLGMNMTTAFNIFIRQSLRIGGIPFKIISDERGFYNKYNQKKLHAAAKRMNEGKYIV
HDILE
MAQINVNIRMDSEVKQEAEQLFDSLGMNMTTAFNIFIRQSLRIGGIPFKIISDERGFYNKYNQKKLHAAAKRMNEGKYIV
HDILE
Download Length: 258 bp
>AT123182 NZ_CP038803:c1843296-1843039 [Treponema putidum]
ATGGCTCAAATAAATGTCAATATAAGAATGGATTCCGAAGTAAAACAAGAGGCTGAACAGCTTTTTGACAGTTTAGGAAT
GAATATGACAACTGCATTTAATATTTTCATTCGTCAATCATTAAGAATCGGCGGTATACCATTTAAAATTATAAGTGATG
AAAGAGGCTTTTATAATAAATATAATCAAAAAAAACTACATGCTGCTGCTAAAAGAATGAATGAAGGGAAATATATAGTG
CATGATATATTGGAATAG
ATGGCTCAAATAAATGTCAATATAAGAATGGATTCCGAAGTAAAACAAGAGGCTGAACAGCTTTTTGACAGTTTAGGAAT
GAATATGACAACTGCATTTAATATTTTCATTCGTCAATCATTAAGAATCGGCGGTATACCATTTAAAATTATAAGTGATG
AAAGAGGCTTTTATAATAAATATAATCAAAAAAAACTACATGCTGCTGCTAAAAGAATGAATGAAGGGAAATATATAGTG
CATGATATATTGGAATAG