Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-DinJ
Location 1944343..1944868 Replicon chromosome
Accession NZ_CP038802
Organism Treponema putidum strain OMZ 847

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag E4N76_RS09230 Protein ID WP_255804911.1
Coordinates 1944343..1944606 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag E4N76_RS09235 Protein ID WP_255804913.1
Coordinates 1944611..1944868 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4N76_RS09200 (E4N76_09355) 1940566..1941372 + 807 WP_245608945.1 hypothetical protein -
E4N76_RS09205 (E4N76_09360) 1941413..1941925 - 513 WP_255804906.1 ClbS/DfsB family four-helix bundle protein -
E4N76_RS09210 (E4N76_09365) 1942002..1942907 - 906 WP_255804907.1 YafY family protein -
E4N76_RS09215 (E4N76_09370) 1943000..1943215 - 216 WP_044977525.1 hypothetical protein -
E4N76_RS09220 (E4N76_09380) 1943559..1943966 - 408 WP_002686861.1 type II toxin-antitoxin system VapC family toxin -
E4N76_RS09225 (E4N76_09385) 1943950..1944228 - 279 WP_044977527.1 hypothetical protein -
E4N76_RS09230 (E4N76_09390) 1944343..1944606 - 264 WP_255804911.1 Txe/YoeB family addiction module toxin Toxin
E4N76_RS09235 (E4N76_09395) 1944611..1944868 - 258 WP_255804913.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
E4N76_RS09240 (E4N76_09400) 1945243..1946511 + 1269 WP_255804915.1 OmpA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(6-50)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10510.08 Da        Isoelectric Point: 9.4465

>T123178 WP_255804911.1 NZ_CP038802:c1944606-1944343 [Treponema putidum]
MIKAWDEDAWMDYVYWQTEDKKTLKRINMLIKDIERNGHNGLGSPEPLKENLSGFWSRRIDKKNRLVYRIVDNVIQIIQC
RTHYGEK

Download         Length: 264 bp

>T123178 NZ_CP038802:c1944606-1944343 [Treponema putidum]
ATGATTAAAGCATGGGATGAAGATGCGTGGATGGATTATGTCTATTGGCAAACAGAAGATAAAAAAACATTAAAAAGAAT
CAATATGTTGATTAAAGATATAGAAAGAAATGGTCATAATGGCTTAGGCAGTCCTGAGCCATTAAAGGAAAATCTGTCAG
GATTCTGGAGCCGCAGGATCGATAAAAAAAATAGATTGGTTTATAGAATAGTCGATAATGTGATACAAATAATTCAGTGT
AGAACCCATTATGGTGAAAAATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9880.42 Da        Isoelectric Point: 9.5364

>AT123178 WP_255804913.1 NZ_CP038802:c1944868-1944611 [Treponema putidum]
MAQINVNIRMDSEVKQEAEQLFDSLGMNMTTAFNIFIRQSLRIGGIPFKIISDERGFYNKYNQKKLHAAAKRMNEGKYIV
HDILE

Download         Length: 258 bp

>AT123178 NZ_CP038802:c1944868-1944611 [Treponema putidum]
ATGGCTCAAATAAATGTCAATATAAGAATGGATTCCGAAGTAAAACAAGAGGCTGAACAGCTTTTTGACAGTTTAGGAAT
GAATATGACAACTGCATTTAATATTTTCATTCGTCAATCATTAAGAATCGGCGGTATACCATTTAAAATTATAAGTGATG
AAAGAGGCTTTTATAATAAATATAATCAAAAAAAACTACATGCTGCTGCTAAAAGAATGAATGAAGGGAAATATATAGTG
CATGATATATTGGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References