Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 190057..190591 Replicon plasmid pArsFIN2
Accession NZ_CP038614
Organism Arsenophonus nasoniae strain FIN

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ArsFIN_RS20615 Protein ID WP_135678429.1
Coordinates 190057..190338 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ArsFIN_RS20620 Protein ID WP_135678431.1
Coordinates 190325..190591 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ArsFIN_RS20590 185512..186671 + 1160 WP_135677411.1 IS3 family transposase -
ArsFIN_RS20595 186700..187347 - 648 Protein_214 IS21 family transposase -
ArsFIN_RS20600 187437..188348 + 912 Protein_215 transposase -
ArsFIN_RS20605 188903..189163 + 261 WP_135678472.1 hypothetical protein -
ArsFIN_RS20610 189364..189969 + 606 WP_135678426.1 recombinase family protein -
ArsFIN_RS20615 190057..190338 - 282 WP_135678429.1 type II toxin-antitoxin system YafQ family toxin Toxin
ArsFIN_RS20620 190325..190591 - 267 WP_135678431.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
ArsFIN_RS20625 190859..192076 + 1218 WP_167876730.1 DUF1073 domain-containing protein -
ArsFIN_RS20630 192033..192911 + 879 WP_167876731.1 hypothetical protein -
ArsFIN_RS20635 192898..194085 + 1188 WP_135678437.1 DUF2213 domain-containing protein -
ArsFIN_RS20640 194085..194564 + 480 WP_135678439.1 hypothetical protein -
ArsFIN_RS20645 194568..195536 + 969 WP_135678441.1 DUF2184 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..222851 222851


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10884.58 Da        Isoelectric Point: 10.4639

>T123079 WP_135678429.1 NZ_CP038614:c190338-190057 [Arsenophonus nasoniae]
MRTIERSVTFKRDYKREAKGRHRNNLDKVLISVITSLVIDEPLKTSHRDHDLIGKWSGHRECHIKPDLLLIYRKPDSETL
QLVRLGSHAQLFG

Download         Length: 282 bp

>T123079 NZ_CP038614:c190338-190057 [Arsenophonus nasoniae]
ATGAGGACAATTGAGCGTTCAGTAACATTTAAACGTGACTACAAACGAGAAGCCAAAGGACGGCATCGCAATAACCTTGA
TAAAGTCCTCATATCCGTTATCACTTCTCTAGTGATTGATGAACCACTCAAAACATCCCATCGTGATCATGATTTAATCG
GTAAATGGTCAGGTCATAGAGAATGTCATATAAAACCTGATTTGTTATTAATATATCGAAAACCAGATAGTGAAACCCTC
CAACTTGTCAGGTTGGGATCACACGCTCAGTTATTCGGCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9816.24 Da        Isoelectric Point: 6.4627

>AT123079 WP_135678431.1 NZ_CP038614:c190591-190325 [Arsenophonus nasoniae]
MRHSETYVRARIDANTKQRATAALEAMGLSVSDAIRLLMLRVADEQRLPFDVKVPNTTTKKAIAELEEGKGKQFDCVTAL
MADLHEDN

Download         Length: 267 bp

>AT123079 NZ_CP038614:c190591-190325 [Arsenophonus nasoniae]
ATGCGTCATTCTGAAACCTATGTCCGCGCCCGCATTGACGCGAATACTAAACAACGCGCCACCGCTGCACTTGAAGCGAT
GGGGCTTTCTGTTTCTGATGCCATTAGGTTGTTGATGCTTCGCGTAGCTGATGAACAACGTTTGCCATTTGATGTCAAAG
TCCCGAACACCACAACCAAAAAGGCAATAGCTGAATTAGAGGAAGGAAAGGGAAAACAGTTTGACTGTGTGACAGCATTG
ATGGCGGATTTACATGAGGACAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References