Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 132169..132704 Replicon plasmid pArsFIN2
Accession NZ_CP038614
Organism Arsenophonus nasoniae strain FIN

Toxin (Protein)


Gene name relE Uniprot ID A0A4P7L9F7
Locus tag ArsFIN_RS20310 Protein ID WP_026824095.1
Coordinates 132169..132456 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4V1BXI0
Locus tag ArsFIN_RS20315 Protein ID WP_026824096.1
Coordinates 132453..132704 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ArsFIN_RS20295 128596..129755 + 1160 WP_135678367.1 IS3 family transposase -
ArsFIN_RS20300 130115..131317 - 1203 WP_135678014.1 IS91 family transposase -
ArsFIN_RS20305 131327..131785 - 459 WP_135678330.1 hypothetical protein -
ArsFIN_RS20310 132169..132456 - 288 WP_026824095.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ArsFIN_RS20315 132453..132704 - 252 WP_026824096.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ArsFIN_RS20320 132786..133679 + 894 WP_081700726.1 type II secretion system F family protein -
ArsFIN_RS20325 133739..134197 + 459 WP_210409124.1 hypothetical protein -
ArsFIN_RS20330 134207..135409 + 1203 WP_135678369.1 IS91 family transposase -
ArsFIN_RS20335 135565..136809 - 1245 WP_026823913.1 oligosaccharide flippase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..222851 222851
- flank IS/Tn - - 128596..128910 314


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11252.32 Da        Isoelectric Point: 10.9743

>T123078 WP_026824095.1 NZ_CP038614:c132456-132169 [Arsenophonus nasoniae]
MIYKVKFRTDALKEWNNLDRSIQQQFARKLKKCAENPHIPAARLRGMQNCYKIKLRSSGFRLVYQIFKDELIIAVVAVGK
REHSEVYKLASKRLR

Download         Length: 288 bp

>T123078 NZ_CP038614:c132456-132169 [Arsenophonus nasoniae]
ATGATCTACAAGGTTAAGTTCAGAACTGATGCACTCAAAGAATGGAACAATCTTGATCGTTCCATTCAACAGCAATTCGC
CAGGAAGTTGAAGAAATGCGCTGAGAATCCGCATATTCCAGCAGCCAGGCTGAGAGGAATGCAAAATTGCTATAAGATTA
AACTCAGATCATCTGGCTTCAGACTTGTTTACCAAATCTTTAAGGATGAGTTAATCATTGCAGTTGTTGCCGTTGGAAAA
CGTGAACATAGTGAAGTTTATAAACTTGCTAGCAAACGACTGCGTTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9362.58 Da        Isoelectric Point: 4.0543

>AT123078 WP_026824096.1 NZ_CP038614:c132704-132453 [Arsenophonus nasoniae]
MPTTILSTTTASITELKTNPMATVNSGDGYPVAILNRNQPAFYCIPAELYEQMLEFIDDQELANLVKERAEQTLHDVNLD
RYL

Download         Length: 252 bp

>AT123078 NZ_CP038614:c132704-132453 [Arsenophonus nasoniae]
ATGCCAACAACCATTCTTAGTACAACAACAGCTAGCATTACGGAATTGAAAACAAACCCTATGGCAACAGTCAATTCAGG
AGATGGGTATCCGGTTGCAATTTTGAATCGTAATCAACCTGCGTTTTACTGCATTCCTGCCGAGTTATATGAACAAATGT
TAGAGTTTATTGATGACCAGGAATTAGCAAACCTAGTCAAAGAGCGTGCAGAGCAGACATTACATGATGTCAATCTGGAT
CGTTACTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7L9F7

Antitoxin

Source ID Structure
AlphaFold DB A0A4V1BXI0

References