Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3151504..3152132 Replicon chromosome
Accession NZ_CP038613
Organism Arsenophonus nasoniae strain FIN

Toxin (Protein)


Gene name Hha Uniprot ID D2TWD5
Locus tag ArsFIN_RS16065 Protein ID WP_026821483.1
Coordinates 3151929..3152132 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID A0A4P7KX12
Locus tag ArsFIN_RS16060 Protein ID WP_026821484.1
Coordinates 3151504..3151872 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ArsFIN_RS16050 3146658..3147821 + 1164 WP_026821486.1 efflux RND transporter periplasmic adaptor subunit -
ArsFIN_RS16055 3147864..3150983 + 3120 WP_026821485.1 multidrug efflux RND transporter permease subunit -
ArsFIN_RS16060 3151504..3151872 + 369 WP_026821484.1 Hha toxicity modulator TomB Antitoxin
ArsFIN_RS16065 3151929..3152132 + 204 WP_026821483.1 hemolysin expression modulator Hha Toxin
ArsFIN_RS16075 3152930..3154710 - 1781 Protein_3162 SmdB family multidrug efflux ABC transporter permease/ATP-binding protein -
ArsFIN_RS16080 3154703..3156374 - 1672 Protein_3163 SmdA family multidrug ABC transporter permease/ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8133.45 Da        Isoelectric Point: 6.9767

>T123077 WP_026821483.1 NZ_CP038613:3151929-3152132 [Arsenophonus nasoniae]
MTKIDYLMRLRKCTTIETLERVIEKNKYELSEDELELFYSAADHRLAELTMNKLYDKIPSSVWKYVR

Download         Length: 204 bp

>T123077 NZ_CP038613:3151929-3152132 [Arsenophonus nasoniae]
ATGACTAAAATTGACTATCTGATGCGCTTAAGAAAATGTACGACTATCGAAACATTGGAGCGCGTAATCGAAAAAAACAA
ATATGAATTATCTGAAGACGAACTTGAGTTATTTTATTCTGCTGCCGACCATAGGTTAGCAGAACTCACAATGAATAAAC
TTTATGACAAAATTCCTTCGTCAGTTTGGAAGTATGTTCGCTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14453.41 Da        Isoelectric Point: 5.1197

>AT123077 WP_026821484.1 NZ_CP038613:3151504-3151872 [Arsenophonus nasoniae]
MDEYSPRSYDILVLKYLCDALHRDAMLTLHRTKTHWKNDLGSDQNVKFNVLIDHITDFIGQFKLKYPNNVNLFIFIDEYL
DETYNLFGKPVMSLTDISDWQKMNEHLSEILTNDIKYSLSNT

Download         Length: 369 bp

>AT123077 NZ_CP038613:3151504-3151872 [Arsenophonus nasoniae]
ATGGATGAGTACTCACCAAGGAGTTATGACATCTTAGTGCTAAAGTATTTATGTGATGCTCTACATCGTGATGCGATGTT
AACTTTGCATAGGACAAAAACCCATTGGAAGAATGATCTTGGTTCCGACCAAAACGTTAAATTTAATGTATTAATTGATC
ATATCACAGATTTTATTGGTCAATTTAAATTAAAATATCCGAATAACGTAAATCTTTTTATTTTTATTGACGAATATTTG
GATGAAACTTATAACCTATTTGGTAAACCTGTAATGAGCCTAACAGATATTTCTGATTGGCAAAAAATGAATGAGCATTT
GTCTGAAATATTAACAAATGATATAAAGTATTCATTAAGTAACACTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB D2TWD5

Antitoxin

Source ID Structure
AlphaFold DB A0A4P7KX12

References