Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2895877..2896531 Replicon chromosome
Accession NZ_CP038613
Organism Arsenophonus nasoniae strain FIN

Toxin (Protein)


Gene name cptA Uniprot ID A0A4P7L3M1
Locus tag ArsFIN_RS14710 Protein ID WP_026821813.1
Coordinates 2895877..2896284 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A4P7KWA0
Locus tag ArsFIN_RS14715 Protein ID WP_026821812.1
Coordinates 2896265..2896531 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ArsFIN_RS14695 2891559..2892758 + 1200 WP_135677934.1 IS91 family transposase -
ArsFIN_RS14700 2893543..2894856 + 1314 WP_051296926.1 S8 family serine peptidase -
ArsFIN_RS14705 2895343..2895861 + 519 WP_026821814.1 flavodoxin FldB -
ArsFIN_RS14710 2895877..2896284 - 408 WP_026821813.1 protein YgfX Toxin
ArsFIN_RS14715 2896265..2896531 - 267 WP_026821812.1 FAD assembly factor SdhE Antitoxin
ArsFIN_RS14720 2896791..2897777 + 987 WP_051296925.1 tRNA-modifying protein YgfZ -
ArsFIN_RS14725 2898632..2898871 - 240 WP_026821810.1 hypothetical protein -
ArsFIN_RS14730 2899199..2900035 - 837 WP_026821809.1 hypothetical protein -
ArsFIN_RS14735 2900127..2900984 - 858 WP_026821808.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15888.82 Da        Isoelectric Point: 10.8101

>T123076 WP_026821813.1 NZ_CP038613:c2896284-2895877 [Arsenophonus nasoniae]
VVLWKFNINVSWLTQLFSTGVHVGIGLLVFFSSWPPNNLVTWLIATLLIVASWVRSQKNISRCKGSIVLLNGNKIQWKKS
EWLIVKKPWFCFFGVKLTLRSWQCNKRIRLWIASDSMPEEEWRNLNQLLLQYPDI

Download         Length: 408 bp

>T123076 NZ_CP038613:c2896284-2895877 [Arsenophonus nasoniae]
GTGGTTCTTTGGAAATTTAATATCAATGTTTCGTGGCTGACGCAGCTTTTTTCAACGGGTGTTCATGTGGGAATTGGCTT
GTTAGTTTTCTTTTCATCTTGGCCACCAAATAATCTGGTCACTTGGTTGATAGCGACCTTATTGATTGTGGCAAGTTGGG
TAAGGAGTCAAAAAAATATTAGTCGTTGTAAAGGTAGCATAGTTTTACTTAATGGTAATAAGATACAGTGGAAAAAAAGC
GAATGGCTGATTGTTAAAAAACCTTGGTTTTGTTTTTTTGGTGTAAAACTTACTCTTCGTTCATGGCAATGTAATAAGCG
GATTCGGTTATGGATTGCTTCAGATAGTATGCCAGAAGAGGAATGGCGGAATTTAAATCAATTGCTGTTGCAGTACCCTG
ATATTTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10612.15 Da        Isoelectric Point: 5.1149

>AT123076 WP_026821812.1 NZ_CP038613:c2896531-2896265 [Arsenophonus nasoniae]
MDINHKPRIHWACRRGMRELDIAIMPFFEYEYDSLTEDEKCLFVRLLECADPDLFNWLMNHGRPDDDGLYHMIQLIQSRN
KQRGSLEI

Download         Length: 267 bp

>AT123076 NZ_CP038613:c2896531-2896265 [Arsenophonus nasoniae]
ATGGATATCAATCATAAACCCAGGATCCACTGGGCATGTCGCAGAGGAATGCGTGAGTTGGACATCGCCATTATGCCTTT
TTTTGAGTATGAATATGATTCACTCACAGAGGATGAGAAATGTCTGTTTGTTCGTTTACTAGAGTGTGCAGATCCTGATT
TGTTCAACTGGTTGATGAATCATGGGCGTCCTGATGATGATGGTCTTTATCATATGATTCAATTGATACAGAGTAGAAAT
AAACAACGTGGTTCTTTGGAAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7L3M1

Antitoxin

Source ID Structure
AlphaFold DB A0A4P7KWA0

References