Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
| Location | 1084987..1086707 | Replicon | chromosome |
| Accession | NZ_CP038499 | ||
| Organism | Dickeya dianthicola strain LAR.16.03.LID | ||
Toxin (Protein)
| Gene name | pmenT | Uniprot ID | - |
| Locus tag | E4659_RS05080 | Protein ID | WP_024108176.1 |
| Coordinates | 1086051..1086707 (-) | Length | 219 a.a. |
Antitoxin (Protein)
| Gene name | pmenA | Uniprot ID | A0A3A4C958 |
| Locus tag | E4659_RS05075 | Protein ID | WP_024104822.1 |
| Coordinates | 1084987..1086054 (-) | Length | 356 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E4659_RS05055 (E4659_05145) | 1080127..1080453 | - | 327 | Protein_987 | molybdopterin-guanine dinucleotide biosynthesis protein MobC | - |
| E4659_RS05060 (E4659_05150) | 1080681..1080863 | - | 183 | WP_024109619.1 | hypothetical protein | - |
| E4659_RS05065 (E4659_05155) | 1081012..1081728 | - | 717 | WP_024104820.1 | SprT family zinc-dependent metalloprotease | - |
| E4659_RS05070 (E4659_05160) | 1081728..1084823 | - | 3096 | WP_024108175.1 | HsdR family type I site-specific deoxyribonuclease | - |
| E4659_RS05075 (E4659_05165) | 1084987..1086054 | - | 1068 | WP_024104822.1 | macro domain-containing protein | Antitoxin |
| E4659_RS05080 (E4659_05170) | 1086051..1086707 | - | 657 | WP_024108176.1 | DUF4433 domain-containing protein | Toxin |
| E4659_RS05085 (E4659_05175) | 1086710..1087285 | - | 576 | WP_024104824.1 | DarT ssDNA thymidine ADP-ribosyltransferase family protein | - |
| E4659_RS05090 (E4659_05180) | 1087290..1088651 | - | 1362 | WP_024104825.1 | restriction endonuclease subunit S | - |
| E4659_RS05095 (E4659_05185) | 1088651..1091086 | - | 2436 | WP_024108177.1 | type I restriction-modification system subunit M | - |
| E4659_RS05100 (E4659_05190) | 1091126..1091365 | - | 240 | WP_024104827.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1065449..1169789 | 104340 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 219 a.a. Molecular weight: 25204.54 Da Isoelectric Point: 7.0621
>T122999 WP_024108176.1 NZ_CP038499:c1086707-1086051 [Dickeya dianthicola]
VAYDYSANLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAANWINIGNPELINRRAGHPVPAGAGGTLHDYVPFYFTP
FSPMLMNIHSGRGGIKQRPNEEIVILVSSLRTVAAQHVPFVFTDSHAYYHWANYYTELDNLNQIDWPILQRRDFRRDPDD
PARFERYQAEALIWQHCPVTLLSGMVCYNNDVKLHLEQWLSQRNLTMPVHARAGWYFS
VAYDYSANLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAANWINIGNPELINRRAGHPVPAGAGGTLHDYVPFYFTP
FSPMLMNIHSGRGGIKQRPNEEIVILVSSLRTVAAQHVPFVFTDSHAYYHWANYYTELDNLNQIDWPILQRRDFRRDPDD
PARFERYQAEALIWQHCPVTLLSGMVCYNNDVKLHLEQWLSQRNLTMPVHARAGWYFS
Download Length: 657 bp
>T122999 NZ_CP038499:c1086707-1086051 [Dickeya dianthicola]
GTGGCCTATGACTACAGCGCCAATCTCAACCCGGAAAAGGCCCTTATCTGGCGCATTGTCCACCGGGACAACATCCCGTG
GATACTGGACAACGGTCTACACTGCGGCAACAGCCCGGTGCAGGCTGCAAACTGGATCAATATTGGTAACCCGGAGCTTA
TCAACAGACGCGCCGGGCACCCGGTGCCTGCCGGGGCGGGTGGTACGTTGCATGACTATGTGCCGTTTTACTTTACGCCT
TTCTCGCCGATGTTGATGAATATCCACAGCGGGCGCGGCGGCATTAAGCAACGCCCCAATGAGGAAATCGTTATTCTGGT
CAGTAGTCTGCGTACCGTGGCGGCGCAACATGTGCCTTTCGTGTTTACCGACAGCCACGCCTACTATCACTGGGCCAACT
ATTACACCGAGTTGGACAACCTGAACCAAATCGACTGGCCCATTTTACAACGGCGGGATTTTCGCCGTGACCCCGACGAC
CCCGCCAGGTTTGAGCGCTATCAGGCCGAGGCACTGATTTGGCAACACTGCCCTGTCACACTGCTGAGCGGGATGGTTTG
TTACAACAACGACGTCAAGTTACACTTAGAGCAATGGCTGTCGCAACGCAATCTGACAATGCCCGTTCACGCACGGGCCG
GGTGGTACTTCTCATGA
GTGGCCTATGACTACAGCGCCAATCTCAACCCGGAAAAGGCCCTTATCTGGCGCATTGTCCACCGGGACAACATCCCGTG
GATACTGGACAACGGTCTACACTGCGGCAACAGCCCGGTGCAGGCTGCAAACTGGATCAATATTGGTAACCCGGAGCTTA
TCAACAGACGCGCCGGGCACCCGGTGCCTGCCGGGGCGGGTGGTACGTTGCATGACTATGTGCCGTTTTACTTTACGCCT
TTCTCGCCGATGTTGATGAATATCCACAGCGGGCGCGGCGGCATTAAGCAACGCCCCAATGAGGAAATCGTTATTCTGGT
CAGTAGTCTGCGTACCGTGGCGGCGCAACATGTGCCTTTCGTGTTTACCGACAGCCACGCCTACTATCACTGGGCCAACT
ATTACACCGAGTTGGACAACCTGAACCAAATCGACTGGCCCATTTTACAACGGCGGGATTTTCGCCGTGACCCCGACGAC
CCCGCCAGGTTTGAGCGCTATCAGGCCGAGGCACTGATTTGGCAACACTGCCCTGTCACACTGCTGAGCGGGATGGTTTG
TTACAACAACGACGTCAAGTTACACTTAGAGCAATGGCTGTCGCAACGCAATCTGACAATGCCCGTTCACGCACGGGCCG
GGTGGTACTTCTCATGA
Antitoxin
Download Length: 356 a.a. Molecular weight: 40767.89 Da Isoelectric Point: 5.4873
>AT122999 WP_024104822.1 NZ_CP038499:c1086054-1084987 [Dickeya dianthicola]
MMTYTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMKAYALACKQKQVTTGKMFITETDELMGPRWIVNFPTK
QHWRADSRMEWIEDGLQDLRRFLIEEKVQSIAIPPLGAGNGGLNWSDVQARIESALGDLQDTEILIYEPTEKYQNVAKST
GVKKLTPARAMIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHNYGPYAPNLNHLLNALDGTYLK
AEKRIPDSQPLDVIWFNDREKEHINLWLNNEAKAWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGECQPTLDSVKEG
LHQWPAGERWASRKMKLFDDKNLQFAINRVMEFHC
MMTYTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMKAYALACKQKQVTTGKMFITETDELMGPRWIVNFPTK
QHWRADSRMEWIEDGLQDLRRFLIEEKVQSIAIPPLGAGNGGLNWSDVQARIESALGDLQDTEILIYEPTEKYQNVAKST
GVKKLTPARAMIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHNYGPYAPNLNHLLNALDGTYLK
AEKRIPDSQPLDVIWFNDREKEHINLWLNNEAKAWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGECQPTLDSVKEG
LHQWPAGERWASRKMKLFDDKNLQFAINRVMEFHC
Download Length: 1068 bp
>AT122999 NZ_CP038499:c1086054-1084987 [Dickeya dianthicola]
ATGATGACATATACACAAGGCAATTTACTGGACGCGCCCGTGGAAGCACTGGTGAATACGGTGAATACCGTCGGTGTCAT
GGGTAAAGGCATCGCGCTGATGTTCAAAGAGCGCTTCCCCGATAATATGAAAGCCTATGCACTCGCCTGTAAACAAAAGC
AGGTGACGACTGGCAAAATGTTTATCACTGAAACCGACGAGCTGATGGGGCCACGCTGGATCGTCAACTTCCCTACCAAG
CAGCACTGGCGCGCCGACTCTCGCATGGAGTGGATTGAAGACGGCTTACAGGACTTACGTCGCTTTTTGATCGAAGAGAA
AGTGCAGTCCATCGCCATTCCTCCGCTGGGGGCGGGAAACGGCGGCCTGAACTGGTCGGACGTGCAGGCGCGGATTGAAT
CTGCGCTGGGCGACCTTCAGGACACGGAAATCCTGATTTATGAGCCTACCGAAAAATACCAAAACGTCGCCAAGAGTACC
GGCGTAAAAAAGCTCACCCCCGCCAGAGCGATGATCGCTGAACTGGTGCGCCGCTACTGGGTGCTGGGCATGGAGTGCAG
CCTGCTGGAAATCCAGAAGCTGGCATGGCTGTTACAACGCGCCATTGAACAGCACCAGCAGGAGGACGTGCTAAAACTGC
GGTTTGAGGCACACAATTATGGCCCGTATGCCCCCAACCTGAACCATCTGCTTAACGCGCTGGACGGCACCTATCTGAAG
GCCGAGAAACGCATCCCGGACAGCCAGCCGCTGGACGTGATCTGGTTTAACGATCGGGAAAAAGAACACATTAATCTCTG
GCTGAATAACGAGGCCAAAGCGTGGCTACCGGCGCTTGAGCAGGTCAGCCAGTTGATTGACGGCTTTGAATCGCCGTTTG
GTCTGGAGCTGCTGGCGACCGTTGACTGGCTGCTGACCCGAGGAGAGTGCCAGCCCACGCTGGATTCCGTGAAAGAGGGG
CTACACCAGTGGCCTGCCGGTGAACGCTGGGCCAGCCGTAAGATGAAGCTCTTTGACGACAAAAATCTGCAATTTGCCAT
AAACCGTGTCATGGAGTTCCATTGCTGA
ATGATGACATATACACAAGGCAATTTACTGGACGCGCCCGTGGAAGCACTGGTGAATACGGTGAATACCGTCGGTGTCAT
GGGTAAAGGCATCGCGCTGATGTTCAAAGAGCGCTTCCCCGATAATATGAAAGCCTATGCACTCGCCTGTAAACAAAAGC
AGGTGACGACTGGCAAAATGTTTATCACTGAAACCGACGAGCTGATGGGGCCACGCTGGATCGTCAACTTCCCTACCAAG
CAGCACTGGCGCGCCGACTCTCGCATGGAGTGGATTGAAGACGGCTTACAGGACTTACGTCGCTTTTTGATCGAAGAGAA
AGTGCAGTCCATCGCCATTCCTCCGCTGGGGGCGGGAAACGGCGGCCTGAACTGGTCGGACGTGCAGGCGCGGATTGAAT
CTGCGCTGGGCGACCTTCAGGACACGGAAATCCTGATTTATGAGCCTACCGAAAAATACCAAAACGTCGCCAAGAGTACC
GGCGTAAAAAAGCTCACCCCCGCCAGAGCGATGATCGCTGAACTGGTGCGCCGCTACTGGGTGCTGGGCATGGAGTGCAG
CCTGCTGGAAATCCAGAAGCTGGCATGGCTGTTACAACGCGCCATTGAACAGCACCAGCAGGAGGACGTGCTAAAACTGC
GGTTTGAGGCACACAATTATGGCCCGTATGCCCCCAACCTGAACCATCTGCTTAACGCGCTGGACGGCACCTATCTGAAG
GCCGAGAAACGCATCCCGGACAGCCAGCCGCTGGACGTGATCTGGTTTAACGATCGGGAAAAAGAACACATTAATCTCTG
GCTGAATAACGAGGCCAAAGCGTGGCTACCGGCGCTTGAGCAGGTCAGCCAGTTGATTGACGGCTTTGAATCGCCGTTTG
GTCTGGAGCTGCTGGCGACCGTTGACTGGCTGCTGACCCGAGGAGAGTGCCAGCCCACGCTGGATTCCGTGAAAGAGGGG
CTACACCAGTGGCCTGCCGGTGAACGCTGGGCCAGCCGTAAGATGAAGCTCTTTGACGACAAAAATCTGCAATTTGCCAT
AAACCGTGTCATGGAGTTCCATTGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|