Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 724258..724936 Replicon chromosome
Accession NZ_CP038499
Organism Dickeya dianthicola strain LAR.16.03.LID

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag E4659_RS03385 Protein ID WP_024104636.1
Coordinates 724505..724936 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A3A4CJ89
Locus tag E4659_RS03380 Protein ID WP_024104635.1
Coordinates 724258..724524 (+) Length 89 a.a.

Genomic Context

E4659_RS03370E4659_RS03380E4659_RS03385E4659_RS03400E4659_RS03405E4659_RS03365E4659_RS03375E4659_RS03390E4659_RS03395
Location: 722223..722873 (651 bp)
Type: Others
Protein ID: WP_024104633.1
Location: 724258..724524 (267 bp)
Type: Antitoxin
Protein ID: WP_024104635.1
Location: 724505..724936 (432 bp)
Type: Toxin
Protein ID: WP_024104636.1
Location: 727266..728165 (900 bp)
Type: Others
Protein ID: WP_024104639.1
Location: 728255..728971 (717 bp)
Type: Others
Protein ID: WP_024104640.1
Location: 721342..721950 (609 bp)
Type: Others
Protein ID: WP_024108232.1
Location: 722964..723944 (981 bp)
Type: Others
Protein ID: WP_024104634.1
Location: 725031..725549 (519 bp)
Type: Others
Protein ID: WP_024104637.1
Location: 725678..727003 (1326 bp)
Type: Others
Protein ID: WP_024104638.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
E4659_RS03365 (E4659_03395)721342..721950-609WP_024108232.1HD domain-containing protein-
E4659_RS03370 (E4659_03400)722223..722873+651WP_024104633.1hemolysin III family protein-
E4659_RS03375 (E4659_03405)722964..723944-981WP_024104634.1tRNA-modifying protein YgfZ-
E4659_RS03380 (E4659_03410)724258..724524+267WP_024104635.1FAD assembly factor SdhEAntitoxin
E4659_RS03385 (E4659_03415)724505..724936+432WP_024104636.1protein YgfXToxin
E4659_RS03390 (E4659_03420)725031..725549-519WP_024104637.1flavodoxin FldB-
E4659_RS03395 (E4659_03425)725678..727003-1326WP_024104638.1MFS transporter-
E4659_RS03400 (E4659_03430)727266..728165+900WP_024104639.1site-specific tyrosine recombinase XerD-
E4659_RS03405 (E4659_03435)728255..728971+717WP_024104640.1bifunctional protein-disulfide isomerase/oxidoreductase DsbC-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 16839.52 Da        Isoelectric Point: 11.7737

>T122997 WP_024104636.1 NZ_CP038499:724505-724936 [Dickeya dianthicola]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWSDGYAPLWLGLVTLVVFGFVRSQRIIKSRQGEISLHGENQLHWQQR
DWQIVRRPWVMRNGVLLSLRATNGKGHQRLWLASDSMGNEEWRLLRQLLQQHPLQGTESSRHH

Download         Length: 432 bp

>T122997 NZ_CP038499:724505-724936 [Dickeya dianthicola]
GTGGCCCAGTGGCAATGTGATTTACGCGTATCCTGGCGCATGCAGCTGTTTTCGCTGCTGACGCACGGGTTTCTGGTGCT
GATGATCCTGCTGGCGCCCTGGTCGGACGGCTATGCGCCGCTGTGGTTGGGCCTGGTGACGCTGGTGGTGTTCGGTTTCG
TGCGCAGTCAGCGCATCATCAAGTCGCGTCAGGGGGAAATTTCCCTGCATGGGGAAAACCAACTGCACTGGCAGCAGCGT
GACTGGCAGATAGTTCGGCGCCCGTGGGTAATGCGCAACGGCGTGTTGCTGTCATTGCGGGCAACGAATGGCAAAGGGCA
TCAGCGCTTGTGGCTGGCGTCAGACAGTATGGGTAACGAAGAATGGCGGCTGTTGCGCCAACTGTTGCAGCAGCATCCGT
TGCAGGGAACCGAATCCTCCCGCCATCATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10471.02 Da        Isoelectric Point: 6.0666

>AT122997 WP_024104635.1 NZ_CP038499:724258-724524 [Dickeya dianthicola]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKLHFIRLLQCDDPDLFNWLMNHGEPVDPALKRMVSLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT122997 NZ_CP038499:724258-724524 [Dickeya dianthicola]
ATGGACATCAATAACAAATCACGTATTCACTGGGCGTGCAGACGCGGAATGCGTGAACTGGACATCTCCATCATGCCGTT
TTTCGAGCATGAATATGACACGCTGAGCGACGACGACAAGCTGCACTTCATTCGTCTGCTGCAGTGCGATGATCCCGACT
TGTTCAACTGGCTGATGAATCATGGCGAGCCGGTAGATCCGGCGCTGAAACGCATGGTTTCCCTTATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A3A4CJ89

References