Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 2982032..2982756 Replicon chromosome
Accession NZ_CP038498
Organism Pectobacterium punjabense strain SS95

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag E2566_RS13540 Protein ID WP_107170982.1
Coordinates 2982032..2982352 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag E2566_RS13545 Protein ID WP_129705773.1
Coordinates 2982421..2982756 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2566_RS13510 2979030..2979248 + 219 WP_107170987.1 KTSC domain-containing protein -
E2566_RS13515 2979465..2979821 + 357 WP_107170986.1 hypothetical protein -
E2566_RS13520 2980029..2980133 + 105 Protein_2640 transposase -
E2566_RS13525 2980329..2980757 - 429 WP_107170984.1 tRNA(fMet)-specific endonuclease VapC -
E2566_RS13530 2980757..2980987 - 231 WP_107170983.1 antitoxin -
E2566_RS13535 2981081..2981914 - 834 WP_107170988.1 DUF4942 domain-containing protein -
E2566_RS13540 2982032..2982352 - 321 WP_107170982.1 TA system toxin CbtA family protein Toxin
E2566_RS13545 2982421..2982756 - 336 WP_129705773.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
E2566_RS13550 2982796..2983269 - 474 WP_107169985.1 DNA repair protein RadC -
E2566_RS13555 2983392..2983742 - 351 WP_107169984.1 hypothetical protein -
E2566_RS13560 2983800..2984633 - 834 WP_107169983.1 hypothetical protein -
E2566_RS13565 2984780..2984938 - 159 WP_165800660.1 hypothetical protein -
E2566_RS13570 2985122..2986009 - 888 WP_107169982.1 50S ribosome-binding GTPase -
E2566_RS13575 2986104..2987036 - 933 WP_107169981.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12005.75 Da        Isoelectric Point: 5.0492

>T122994 WP_107170982.1 NZ_CP038498:c2982352-2982032 [Pectobacterium punjabense]
MQTSPAIPPREDNPCPSPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQAHIDAGITLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKA

Download         Length: 321 bp

>T122994 NZ_CP038498:c2982352-2982032 [Pectobacterium punjabense]
ATGCAAACATCACCGGCAATCCCTCCACGGGAGGATAACCCCTGTCCGTCACCTATAGCCGTCTGGCAGCAACTACTGAC
TTACCTGCTGGAAAAGCACTACGGCCTGACGCTGAACGACACGCCGTTCTGTGAGGAAAACGTGATTCAGGCGCATATCG
ATGCTGGCATCACGCTGGTCAATGCCGTCAATTTTCTGGTGGAGAAATACGAACTGGTGCGTATCGATCGCAACGGCTTT
AACTGGCAGGAGCAATCGCCGTTTCTTACCGCCGTTGATGTTCTCCGTGCCAGACGTGCTACTGGCTTGCTCAAGGCATA
A

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12447.19 Da        Isoelectric Point: 5.7100

>AT122994 WP_129705773.1 NZ_CP038498:c2982756-2982421 [Pectobacterium punjabense]
MPSSETPEWGLKSAVTPRFGARLVQEGNRLHYLADRASIVGTFSKTETQSLERCFPELIKLLEQKLRMGELNPRQQNCVT
LHCNEWICEADTLGSVGYVYIVIYPSSAAAE

Download         Length: 336 bp

>AT122994 NZ_CP038498:c2982756-2982421 [Pectobacterium punjabense]
ATGCCATCATCGGAGACCCCGGAATGGGGACTAAAAAGTGCTGTCACGCCGCGATTCGGAGCCAGACTGGTGCAGGAAGG
TAACCGTCTGCACTATCTGGCAGACCGGGCCAGCATTGTCGGTACGTTCAGTAAAACAGAAACCCAAAGTCTGGAACGTT
GCTTCCCTGAGCTAATTAAGTTGTTGGAACAGAAGCTACGCATGGGGGAACTGAATCCCCGTCAGCAGAACTGCGTCACG
CTGCATTGCAACGAATGGATCTGTGAAGCCGATACGCTGGGCAGTGTTGGCTACGTGTATATTGTTATCTATCCCTCTTC
GGCAGCAGCAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References