Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2980329..2980987 Replicon chromosome
Accession NZ_CP038498
Organism Pectobacterium punjabense strain SS95

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag E2566_RS13525 Protein ID WP_107170984.1
Coordinates 2980329..2980757 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag E2566_RS13530 Protein ID WP_107170983.1
Coordinates 2980757..2980987 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2566_RS13495 2975681..2975884 - 204 WP_107167800.1 protein DsrB -
E2566_RS13500 2976095..2977507 + 1413 WP_107167801.1 diguanylate cyclase -
E2566_RS13510 2979030..2979248 + 219 WP_107170987.1 KTSC domain-containing protein -
E2566_RS13515 2979465..2979821 + 357 WP_107170986.1 hypothetical protein -
E2566_RS13520 2980029..2980133 + 105 Protein_2640 transposase -
E2566_RS13525 2980329..2980757 - 429 WP_107170984.1 tRNA(fMet)-specific endonuclease VapC Toxin
E2566_RS13530 2980757..2980987 - 231 WP_107170983.1 antitoxin Antitoxin
E2566_RS13535 2981081..2981914 - 834 WP_107170988.1 DUF4942 domain-containing protein -
E2566_RS13540 2982032..2982352 - 321 WP_107170982.1 TA system toxin CbtA family protein -
E2566_RS13545 2982421..2982756 - 336 WP_129705773.1 type IV toxin-antitoxin system YeeU family antitoxin -
E2566_RS13550 2982796..2983269 - 474 WP_107169985.1 DNA repair protein RadC -
E2566_RS13555 2983392..2983742 - 351 WP_107169984.1 hypothetical protein -
E2566_RS13560 2983800..2984633 - 834 WP_107169983.1 hypothetical protein -
E2566_RS13565 2984780..2984938 - 159 WP_165800660.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-54)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15889.11 Da        Isoelectric Point: 7.2742

>T122993 WP_107170984.1 NZ_CP038498:c2980757-2980329 [Pectobacterium punjabense]
MLKYLLDTNICIYTIKNKPQEVRDAFYRHYGQFAISSITLMELIYGAEKSVNPEKNLAVIEGFSARLEVQTYGFDAAVHT
GQIRAELARQGTPIGPYDAMLAGHARSAGLILVTNNVREFERVPGLRVENWVGRQADNSQSL

Download         Length: 429 bp

>T122993 NZ_CP038498:c2980757-2980329 [Pectobacterium punjabense]
ATGCTGAAATATCTACTTGATACCAATATCTGTATTTACACTATCAAGAACAAACCGCAAGAAGTCAGGGATGCTTTCTA
CCGCCATTACGGGCAGTTTGCTATCAGTTCTATCACGCTGATGGAACTGATTTATGGCGCGGAGAAATCGGTAAATCCAG
AGAAGAATCTCGCTGTGATTGAAGGGTTTTCTGCGCGTCTGGAAGTGCAAACTTATGGCTTTGACGCTGCCGTACATACC
GGGCAAATTCGTGCGGAACTGGCAAGACAAGGAACCCCCATCGGCCCGTATGATGCCATGTTAGCCGGTCACGCGCGGTC
CGCAGGTTTAATACTGGTAACGAACAATGTGCGTGAATTTGAGCGTGTGCCAGGATTGCGCGTAGAAAACTGGGTCGGTA
GACAGGCTGACAATAGCCAGTCTTTGTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8625.69 Da        Isoelectric Point: 4.5408

>AT122993 WP_107170983.1 NZ_CP038498:c2980987-2980757 [Pectobacterium punjabense]
MEKTTVFKSNRSQAVRLPKAVALPDDVKQVDIVAIGRTRIITPAGESWDSWFEGEGVTSDFMITREQPNDQIREDF

Download         Length: 231 bp

>AT122993 NZ_CP038498:c2980987-2980757 [Pectobacterium punjabense]
ATGGAAAAAACTACAGTATTTAAAAGCAATCGCAGTCAGGCGGTACGACTCCCTAAAGCGGTTGCACTGCCCGATGATGT
GAAGCAGGTTGATATCGTCGCGATTGGCCGTACACGTATTATCACTCCGGCAGGCGAAAGCTGGGATAGCTGGTTTGAAG
GGGAGGGCGTAACCTCCGACTTTATGATCACCAGAGAGCAACCCAATGATCAGATCCGGGAAGATTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References