Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 569104..569687 Replicon chromosome
Accession NZ_CP038498
Organism Pectobacterium punjabense strain SS95

Toxin (Protein)


Gene name parE Uniprot ID A0A7V8QAI8
Locus tag E2566_RS02610 Protein ID WP_012822278.1
Coordinates 569382..569687 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7V8TMU0
Locus tag E2566_RS02605 Protein ID WP_012822277.1
Coordinates 569104..569394 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2566_RS02585 564164..565426 - 1263 WP_107170802.1 L-rhamnose isomerase -
E2566_RS02590 565423..566913 - 1491 WP_107170803.1 rhamnulokinase -
E2566_RS02595 567282..568121 + 840 WP_107170804.1 HTH-type transcriptional activator RhaS -
E2566_RS02600 568146..569000 + 855 WP_107170805.1 helix-turn-helix domain-containing protein -
E2566_RS02605 569104..569394 + 291 WP_012822277.1 ribbon-helix-helix protein, CopG family Antitoxin
E2566_RS02610 569382..569687 + 306 WP_012822278.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E2566_RS02615 569747..571435 - 1689 WP_107170806.1 ABC transporter ATP-binding protein -
E2566_RS02620 571432..572298 - 867 WP_107170807.1 ABC transporter permease -
E2566_RS02625 572291..573250 - 960 WP_107170808.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-96)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11634.48 Da        Isoelectric Point: 9.4590

>T122990 WP_012822278.1 NZ_CP038498:569382-569687 [Pectobacterium punjabense]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTDRVVILTVKHQKEAGYQNP

Download         Length: 306 bp

>T122990 NZ_CP038498:569382-569687 [Pectobacterium punjabense]
ATGCCACAAGTGATTGTTTCAGAACGCGCAAGACGTGATTTGCAGCGTCTGCAGGATTTTCTAAAAAACAAAAATGCGCT
GGCTGCGAAAAAGGCCGCTGAAGTTTTGATTCGGGGCATTCGTCAGTTAGAAGCGCTGCCGAATATCGGGCGACCCGTTG
AACATCTCCCTCTTGAATATCAGGAACTGGTGATCGAATTCGGCAGCAGCGGGTACGTGATGCTTTACCGCCATGATGAA
CTGACTGACAGAGTGGTGATCCTGACCGTCAAGCATCAAAAAGAAGCCGGTTACCAAAACCCTTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11097.16 Da        Isoelectric Point: 4.7845

>AT122990 WP_012822277.1 NZ_CP038498:569104-569394 [Pectobacterium punjabense]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEEYQNTGEHITADETVTWL
ESWGSGHEQDAPACHK

Download         Length: 291 bp

>AT122990 NZ_CP038498:569104-569394 [Pectobacterium punjabense]
ATGGCTGACACGCCACGCCAAACCACGACGCTGCGCATCGATCAGGACATTAAAGAACGACTGAAAACGTTGGCCGATGA
CCGCCATAGCTCAGCCCATGCGCTAATGCTGGAAGCCATCGCCGAATACGTGGAGCGTGAAGAAAAACGCAGTCAGTACC
GTAAAGAGGCGCTGGCCGCGTGGGAGGAATACCAGAACACCGGCGAACACATCACCGCTGATGAGACGGTCACCTGGTTA
GAATCCTGGGGTTCTGGGCATGAACAGGATGCGCCTGCATGCCACAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7V8QAI8

Antitoxin

Source ID Structure
AlphaFold DB A0A7V8TMU0

References