Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 520815..521539 Replicon chromosome
Accession NZ_CP038498
Organism Pectobacterium punjabense strain SS95

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag E2566_RS02415 Protein ID WP_107169475.1
Coordinates 521219..521539 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag E2566_RS02410 Protein ID WP_107169474.1
Coordinates 520815..521150 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2566_RS02375 516001..516876 + 876 WP_107169467.1 GTPase family protein -
E2566_RS02380 516961..517782 + 822 WP_107169468.1 DUF945 domain-containing protein -
E2566_RS02385 518008..518706 + 699 WP_107169469.1 DeoR family transcriptional regulator -
E2566_RS02390 518888..519457 + 570 WP_168444514.1 hypothetical protein -
E2566_RS02395 519493..519966 + 474 WP_107169471.1 hypothetical protein -
E2566_RS02400 519984..520217 + 234 WP_107169472.1 hypothetical protein -
E2566_RS02405 520302..520775 + 474 WP_107169473.1 DNA repair protein RadC -
E2566_RS02410 520815..521150 + 336 WP_107169474.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
E2566_RS02415 521219..521539 + 321 WP_107169475.1 TA system toxin CbtA family protein Toxin
E2566_RS02420 521657..522139 + 483 Protein_461 DUF4942 domain-containing protein -
E2566_RS02430 523585..524205 - 621 WP_107170325.1 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12051.77 Da        Isoelectric Point: 5.0492

>T122989 WP_107169475.1 NZ_CP038498:521219-521539 [Pectobacterium punjabense]
MQTSPAIPPREDNPCPSPITVWQQLLTYLLEKHYGLTLNDTPFCEENVIQAHIDAGITLANAVNFLVEKYELVRIDRNGF
NWQEQSPFLTTVDILRARRATGLLKA

Download         Length: 321 bp

>T122989 NZ_CP038498:521219-521539 [Pectobacterium punjabense]
ATGCAAACATCACCGGCAATCCCTCCACGGGAGGATAACCCCTGTCCGTCACCTATAACCGTCTGGCAACAACTGCTGAC
CTACCTGCTGGAAAAGCACTACGGCCTGACGCTGAACGACACACCGTTCTGTGAGGAAAACGTAATTCAGGCGCATATCG
ATGCAGGCATCACGCTGGCCAATGCCGTCAATTTTCTGGTGGAGAAATACGAACTGGTACGCATCGATCGCAACGGCTTT
AACTGGCAGGAGCAATCACCGTTTCTCACGACTGTCGACATCCTTCGCGCCAGACGTGCAACGGGCTTACTTAAGGCATA
A

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12495.24 Da        Isoelectric Point: 5.7100

>AT122989 WP_107169474.1 NZ_CP038498:520815-521150 [Pectobacterium punjabense]
MPSSETPEWGLKSAVTPRFGARLVQEGNRLHYLADRASFIGTFSKTEAQSLERCFPELIKLLEQKLRMGELNPRQQNCVT
LHCNEWICEADTLGSVGYVYIVIYPSSATAE

Download         Length: 336 bp

>AT122989 NZ_CP038498:520815-521150 [Pectobacterium punjabense]
ATGCCATCATCGGAGACCCCGGAATGGGGACTAAAAAGTGCTGTCACTCCGCGATTCGGAGCCAGACTGGTGCAGGAAGG
TAACCGTCTGCACTATCTGGCAGACCGGGCCAGCTTTATCGGTACGTTTAGCAAAACAGAAGCCCAAAGTCTGGAACGTT
GCTTCCCTGAGCTAATTAAGCTGTTGGAACAGAAGCTACGCATGGGGGAACTGAATCCCCGTCAGCAGAACTGCGTCACG
CTGCATTGCAACGAATGGATCTGTGAAGCCGATACGCTGGGCAGTGTTGGCTACGTGTATATTGTTATCTATCCCTCTTC
GGCAACAGCAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References