Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3263291..3263562 Replicon chromosome
Accession NZ_CP038496
Organism Escherichia coli O157:H7 strain TT12A

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3263329..3263432 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3263291..3263562 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E5F08_RS16050 3260448..3261887 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
E5F08_RS16055 3262005..3262241 + 237 WP_001295499.1 DUF1480 family protein -
E5F08_RS16060 3262346..3262537 + 192 WP_001296140.1 YebW family protein -
E5F08_RS16065 3262538..3263194 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 3263291..3263562 + 272 - - Antitoxin
- 3263329..3263432 - 104 - - Toxin
E5F08_RS16070 3263590..3263931 - 342 WP_000976483.1 YebY family protein -
E5F08_RS16075 3263944..3264816 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E5F08_RS16080 3264820..3265194 - 375 WP_000168751.1 CopC domain-containing protein YobA -
E5F08_RS16085 3265333..3265563 + 231 WP_000916763.1 DNA polymerase III subunit theta -
E5F08_RS16090 3265665..3266321 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E5F08_RS16095 3266345..3267007 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T122965 NZ_CP038496:c3263432-3263329 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT122965 NZ_CP038496:3263291-3263562 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References