Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3151786..3152057 Replicon chromosome
Accession NZ_CP038494
Organism Escherichia coli O157:H7 strain TT12B

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3151824..3151927 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3151786..3152057 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E5F07_RS15295 3148943..3150382 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
E5F07_RS15300 3150500..3150736 + 237 WP_001295499.1 DUF1480 family protein -
E5F07_RS15305 3150841..3151032 + 192 WP_001296140.1 YebW family protein -
E5F07_RS15310 3151033..3151689 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 3151786..3152057 + 272 - - Antitoxin
- 3151824..3151927 - 104 - - Toxin
E5F07_RS15315 3152085..3152426 - 342 WP_000976483.1 YebY family protein -
E5F07_RS15320 3152439..3153311 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E5F07_RS15325 3153315..3153689 - 375 WP_000168751.1 CopC domain-containing protein YobA -
E5F07_RS15330 3153828..3154058 + 231 WP_000916763.1 DNA polymerase III subunit theta -
E5F07_RS15335 3154160..3154816 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E5F07_RS15340 3154840..3155502 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T122934 NZ_CP038494:c3151927-3151824 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT122934 NZ_CP038494:3151786-3152057 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References