Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4259230..4259884 Replicon chromosome
Accession NZ_CP038469
Organism Citrobacter tructae strain SNU WT2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag E4Z61_RS21085 Protein ID WP_135324414.1
Coordinates 4259477..4259884 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag E4Z61_RS21080 Protein ID WP_096755798.1
Coordinates 4259230..4259496 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4Z61_RS21055 4254482..4255915 - 1434 WP_135324410.1 6-phospho-beta-glucosidase BglA -
E4Z61_RS21060 4256036..4256764 - 729 WP_135324976.1 MurR/RpiR family transcriptional regulator -
E4Z61_RS21065 4256817..4257128 + 312 WP_135324411.1 N(4)-acetylcytidine aminohydrolase -
E4Z61_RS21070 4257292..4257951 + 660 WP_135324412.1 hemolysin III family protein -
E4Z61_RS21075 4257995..4258975 - 981 WP_135324413.1 tRNA-modifying protein YgfZ -
E4Z61_RS21080 4259230..4259496 + 267 WP_096755798.1 FAD assembly factor SdhE Antitoxin
E4Z61_RS21085 4259477..4259884 + 408 WP_135324414.1 protein YgfX Toxin
E4Z61_RS21090 4259930..4260451 - 522 WP_045447250.1 flavodoxin FldB -
E4Z61_RS21095 4260565..4261461 + 897 WP_135324415.1 site-specific tyrosine recombinase XerD -
E4Z61_RS21100 4261485..4262198 + 714 WP_135324416.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
E4Z61_RS21105 4262204..4263937 + 1734 WP_135324417.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15921.90 Da        Isoelectric Point: 11.5692

>T122906 WP_135324414.1 NZ_CP038469:4259477-4259884 [Citrobacter tructae]
VVQWQSDLRVSWRAQWISLLIHGLVAVLILLMPWPLSYTPLWLILLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWTIVSAPWMMKTGMMLRLRSGTGKRQHLWLAADSMDDAEWRDLRRLILQPSMQK

Download         Length: 408 bp

>T122906 NZ_CP038469:4259477-4259884 [Citrobacter tructae]
GTGGTCCAGTGGCAATCTGATTTACGCGTCTCCTGGCGCGCACAGTGGATTTCGCTGCTCATTCATGGGCTGGTGGCGGT
GCTTATTTTATTGATGCCCTGGCCACTGAGTTACACCCCTTTATGGTTGATTTTGCTCTCTCTGGTGGTGTTCGACAGCG
TGCGCAGTCAGCGCCGTATCAACGCTTGTCAGGGAGAGATTAGACTATTGATGGATGGTCGTCTGCGCTGGCAAGGGCAA
GAATGGACTATCGTTAGCGCACCCTGGATGATGAAAACGGGCATGATGTTGCGCTTGCGGTCAGGTACAGGAAAACGTCA
GCATCTGTGGCTGGCGGCGGACAGTATGGATGATGCCGAGTGGCGGGATTTGCGTCGGTTAATATTACAACCATCGATGC
AGAAATAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10570.10 Da        Isoelectric Point: 5.6311

>AT122906 WP_096755798.1 NZ_CP038469:4259230-4259496 [Citrobacter tructae]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDNLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT122906 NZ_CP038469:4259230-4259496 [Citrobacter tructae]
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGTCGCGGTATGCGTGAGCTGGACATCTCGATCATGCCGTT
TTTCGAACATGAGTATGACAACTTAAGTGATGACGAAAAACGCATCTTTATCCGTTTGCTGGAATGTGATGACCCCGATT
TGTTTAACTGGTTGATGAACCATGGGAAGCCGGCTGATGCACAGCTGGAGCAAATGGTACGGCTTATTCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References