Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1(toxin) |
| Location | 3255341..3255951 | Replicon | chromosome |
| Accession | NZ_CP038469 | ||
| Organism | Citrobacter tructae strain SNU WT2 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | E4Z61_RS16270 | Protein ID | WP_135323668.1 |
| Coordinates | 3255341..3255715 (-) | Length | 125 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | E4Z61_RS16275 | Protein ID | WP_205746870.1 |
| Coordinates | 3255715..3255951 (-) | Length | 79 a.a. |
Genomic Context
Location: 3252844..3253746 (903 bp)
Type: Others
Protein ID: WP_135323665.1
Type: Others
Protein ID: WP_135323665.1
Location: 3253743..3254378 (636 bp)
Type: Others
Protein ID: WP_135323666.1
Type: Others
Protein ID: WP_135323666.1
Location: 3254375..3255304 (930 bp)
Type: Others
Protein ID: WP_135323667.1
Type: Others
Protein ID: WP_135323667.1
Location: 3256158..3257072 (915 bp)
Type: Others
Protein ID: WP_135323669.1
Type: Others
Protein ID: WP_135323669.1
Location: 3255341..3255715 (375 bp)
Type: Toxin
Protein ID: WP_135323668.1
Type: Toxin
Protein ID: WP_135323668.1
Location: 3255715..3255951 (237 bp)
Type: Antitoxin
Protein ID: WP_205746870.1
Type: Antitoxin
Protein ID: WP_205746870.1
Location: 3257112..3258053 (942 bp)
Type: Others
Protein ID: WP_167817561.1
Type: Others
Protein ID: WP_167817561.1
Location: 3258098..3258535 (438 bp)
Type: Others
Protein ID: WP_135323671.1
Type: Others
Protein ID: WP_135323671.1
Location: 3258532..3259404 (873 bp)
Type: Others
Protein ID: WP_135323672.1
Type: Others
Protein ID: WP_135323672.1
Location: 3259398..3259997 (600 bp)
Type: Others
Protein ID: WP_135323673.1
Type: Others
Protein ID: WP_135323673.1
Loading, please wait
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E4Z61_RS16255 | 3252844..3253746 | + | 903 | WP_135323665.1 | formate dehydrogenase O subunit beta | - |
| E4Z61_RS16260 | 3253743..3254378 | + | 636 | WP_135323666.1 | formate dehydrogenase cytochrome b556 subunit | - |
| E4Z61_RS16265 | 3254375..3255304 | + | 930 | WP_135323667.1 | formate dehydrogenase accessory protein FdhE | - |
| E4Z61_RS16270 | 3255341..3255715 | - | 375 | WP_135323668.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| E4Z61_RS16275 | 3255715..3255951 | - | 237 | WP_205746870.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
| E4Z61_RS16280 | 3256158..3257072 | + | 915 | WP_135323669.1 | alpha/beta hydrolase | - |
| E4Z61_RS16285 | 3257112..3258053 | - | 942 | WP_167817561.1 | fatty acid biosynthesis protein FabY | - |
| E4Z61_RS16290 | 3258098..3258535 | - | 438 | WP_135323671.1 | D-tyrosyl-tRNA(Tyr) deacylase | - |
| E4Z61_RS16295 | 3258532..3259404 | - | 873 | WP_135323672.1 | virulence factor BrkB family protein | - |
| E4Z61_RS16300 | 3259398..3259997 | - | 600 | WP_135323673.1 | glucose-1-phosphatase | - |
Associated MGEs
Loading, please wait
MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 125 a.a. Molecular weight: 13799.96 Da Isoelectric Point: 8.5257
>T122905 WP_135323668.1 NZ_CP038469:c3255715-3255341 [Citrobacter tructae]
MANGSALFDTNILIDLFSGRREAKQALEAWPPQNAISLITWMEVMVGAKKYNQEHRTRVAMSAFNVIGVSQEIAQRSVAL
RQEYGMKLPDAIILATAQVHRLELVTRNTKDFAGIPGVVTPYEL
MANGSALFDTNILIDLFSGRREAKQALEAWPPQNAISLITWMEVMVGAKKYNQEHRTRVAMSAFNVIGVSQEIAQRSVAL
RQEYGMKLPDAIILATAQVHRLELVTRNTKDFAGIPGVVTPYEL
Download Length: 375 bp
>T122905 NZ_CP038469:c3255715-3255341 [Citrobacter tructae]
ATGGCTAATGGGTCGGCACTTTTTGACACCAATATTTTAATCGACTTATTCAGTGGGCGGCGCGAAGCAAAACAAGCGTT
AGAAGCATGGCCACCGCAGAATGCGATTAGCCTTATTACCTGGATGGAAGTGATGGTGGGTGCCAAAAAATATAATCAGG
AGCACCGCACGCGCGTTGCGATGAGCGCGTTTAACGTTATTGGTGTATCGCAGGAAATTGCCCAGCGAAGTGTTGCTCTG
CGCCAGGAGTATGGGATGAAACTTCCGGATGCCATTATTCTGGCGACAGCGCAAGTTCATCGCCTTGAACTGGTCACGCG
TAATACAAAGGACTTTGCCGGAATACCGGGCGTGGTGACGCCATACGAATTGTAA
ATGGCTAATGGGTCGGCACTTTTTGACACCAATATTTTAATCGACTTATTCAGTGGGCGGCGCGAAGCAAAACAAGCGTT
AGAAGCATGGCCACCGCAGAATGCGATTAGCCTTATTACCTGGATGGAAGTGATGGTGGGTGCCAAAAAATATAATCAGG
AGCACCGCACGCGCGTTGCGATGAGCGCGTTTAACGTTATTGGTGTATCGCAGGAAATTGCCCAGCGAAGTGTTGCTCTG
CGCCAGGAGTATGGGATGAAACTTCCGGATGCCATTATTCTGGCGACAGCGCAAGTTCATCGCCTTGAACTGGTCACGCG
TAATACAAAGGACTTTGCCGGAATACCGGGCGTGGTGACGCCATACGAATTGTAA
Antitoxin
Download Length: 79 a.a. Molecular weight: 9223.54 Da Isoelectric Point: 4.3894
>AT122905 WP_205746870.1 NZ_CP038469:c3255951-3255715 [Citrobacter tructae]
MMIGLDMGRILLDLSDEMIKRLDDLKVQRNLPRAELLREAVEQYLERQSNTTISNALGLWQGCEEDGVEYQRKLREEW
MMIGLDMGRILLDLSDEMIKRLDDLKVQRNLPRAELLREAVEQYLERQSNTTISNALGLWQGCEEDGVEYQRKLREEW
Download Length: 237 bp
>AT122905 NZ_CP038469:c3255951-3255715 [Citrobacter tructae]
ATGATGATTGGGCTGGATATGGGCAGAATTTTACTCGATTTATCAGATGAAATGATTAAACGACTGGACGATCTCAAAGT
GCAACGCAACCTTCCCCGTGCGGAGTTGTTGCGAGAGGCTGTTGAGCAGTATCTGGAAAGACAGTCAAATACGACTATTT
CCAATGCACTTGGCTTGTGGCAGGGCTGTGAAGAAGACGGTGTGGAATACCAGCGCAAACTGCGTGAGGAGTGGTAA
ATGATGATTGGGCTGGATATGGGCAGAATTTTACTCGATTTATCAGATGAAATGATTAAACGACTGGACGATCTCAAAGT
GCAACGCAACCTTCCCCGTGCGGAGTTGTTGCGAGAGGCTGTTGAGCAGTATCTGGAAAGACAGTCAAATACGACTATTT
CCAATGCACTTGGCTTGTGGCAGGGCTGTGAAGAAGACGGTGTGGAATACCAGCGCAAACTGCGTGAGGAGTGGTAA