Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 1298115..1298629 Replicon chromosome
Accession NZ_CP038440
Organism Brevundimonas sp. MF30-B

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E4M01_RS06560 Protein ID WP_135061670.1
Coordinates 1298115..1298375 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag E4M01_RS06565 Protein ID WP_135061669.1
Coordinates 1298372..1298629 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4M01_RS14410 1293805..1294860 - 1056 WP_209316084.1 OmpA family protein -
E4M01_RS06540 1294857..1295417 - 561 WP_135061674.1 hypothetical protein -
E4M01_RS06545 1295484..1296839 - 1356 WP_135061673.1 glutamate--cysteine ligase -
E4M01_RS06550 1296904..1297356 - 453 WP_135061672.1 potassium channel family protein -
E4M01_RS06555 1297399..1298118 - 720 WP_135061671.1 16S rRNA (uracil(1498)-N(3))-methyltransferase -
E4M01_RS06560 1298115..1298375 - 261 WP_135061670.1 Txe/YoeB family addiction module toxin Toxin
E4M01_RS06565 1298372..1298629 - 258 WP_135061669.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
E4M01_RS06570 1298668..1299831 - 1164 WP_135061668.1 acyl-CoA dehydrogenase family protein -
E4M01_RS06575 1299995..1301776 - 1782 WP_135061667.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -
E4M01_RS06580 1301780..1302265 - 486 WP_135061666.1 MerR family DNA-binding transcriptional regulator -
E4M01_RS06585 1302314..1302523 + 210 WP_135061665.1 DUF2256 domain-containing protein -
E4M01_RS06590 1302468..1302896 - 429 WP_135061664.1 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10336.77 Da        Isoelectric Point: 9.9372

>T122797 WP_135061670.1 NZ_CP038440:c1298375-1298115 [Brevundimonas sp. MF30-B]
MNVVFSARAWTQYLQWQDTDRKALRKLNTLIKECQRNPFTGSGKPEPLKAELSGYWSRRIDQEHRLVYRVASYGLEIVQC
RYHYDR

Download         Length: 261 bp

>T122797 NZ_CP038440:c1298375-1298115 [Brevundimonas sp. MF30-B]
ATGAATGTCGTCTTCTCGGCTCGTGCTTGGACCCAGTATCTCCAGTGGCAGGACACGGACCGCAAGGCGCTCAGGAAACT
CAACACGCTGATCAAGGAGTGTCAGCGCAACCCATTCACTGGATCGGGAAAGCCTGAGCCTCTGAAGGCGGAGCTGTCCG
GCTACTGGTCGCGGCGCATCGATCAAGAGCATCGCCTTGTCTACCGCGTCGCTTCTTACGGCTTGGAGATTGTCCAATGC
CGCTACCACTACGACCGATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9296.48 Da        Isoelectric Point: 4.2340

>AT122797 WP_135061669.1 NZ_CP038440:c1298629-1298372 [Brevundimonas sp. MF30-B]
MNAMSITELRKNLAAAVDRVTADHDYTIITREGGKPAAVLMSLEDFASWQETDYLLRSPANREALMASIAELEAGGGTVR
ELIEE

Download         Length: 258 bp

>AT122797 NZ_CP038440:c1298629-1298372 [Brevundimonas sp. MF30-B]
ATGAACGCCATGTCCATCACCGAACTGCGCAAGAACCTCGCGGCTGCCGTCGATCGGGTGACGGCGGATCACGACTACAC
CATCATCACCCGCGAGGGCGGAAAGCCGGCCGCCGTACTGATGTCGCTTGAGGACTTCGCCTCCTGGCAGGAGACGGACT
ATCTGCTTCGCAGCCCGGCGAACCGAGAAGCGCTCATGGCCTCTATCGCCGAACTTGAAGCAGGCGGCGGAACAGTCCGA
GAGCTTATCGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References