Detailed information of TA system TA122795

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3448509..3448959
• Replicon: chromosome
• Accession: NZ_CP038438
• Organism: Pseudomonas fluorescens strain LBUM677

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: E4T63_RS15705
• Protein ID: WP_098964236.1
• Coordinates: 3448690..3448959 (+)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A031G898
• Locus tag: E4T63_RS15700
• Protein ID: WP_003225628.1
• Coordinates: 3448509..3448700 (+)
• Length: 64 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E4T63_RS15680	3443918..3444886	-	969	WP_135295950.1	Gfo/Idh/MocA family oxidoreductase	-
E4T63_RS15685	3444912..3445799	-	888	WP_135295951.1	Dyp-type peroxidase	-
E4T63_RS15690	3445983..3447080	-	1098	WP_098964234.1	AraC family transcriptional regulator	-
E4T63_RS15695	3447291..3448238	+	948	WP_135295952.1	transporter	-
E4T63_RS15700	3448509..3448700	+	192	WP_003225628.1	hypothetical protein	Antitoxin
E4T63_RS15705	3448690..3448959	+	270	WP_098964236.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10197.73 Da
• Isoelectric Point: 9.7677

>T122795 WP_098964236.1 NZ_CP038438:3448690-3448959 [Pseudomonas fluorescens]
VRVDWRPEARTQLWQTLNYIADRNAVAASQLNAAIEAAISALPLHPYLYRFGKVAGTREIVIHPNYVVVYRVTERIEILN
VLHARQGYP

Nucleotide

• Length: 270 bp

>T122795 NZ_CP038438:3448690-3448959 [Pseudomonas fluorescens]
GTGCGGGTTGACTGGCGACCTGAAGCTCGCACTCAACTCTGGCAAACCCTGAACTACATCGCTGACCGTAACGCCGTTGC
GGCCAGTCAACTGAACGCCGCCATCGAAGCGGCTATCTCCGCCCTCCCACTTCACCCCTACCTTTATCGCTTCGGCAAGG
TCGCCGGCACCCGGGAAATCGTTATCCATCCCAACTACGTCGTGGTTTATCGGGTGACCGAGCGGATCGAAATCCTGAAC
GTATTGCATGCTCGACAAGGGTATCCCTGA

Antitoxin

Protein

• Length: 64 a.a.
• Molecular weight: 7108.96 Da
• Isoelectric Point: 4.4184

>AT122795 WP_003225628.1 NZ_CP038438:3448509-3448700 [Pseudomonas fluorescens]
MSAELSLIVSDFETPEQAASYDRWFRAQVQASMDDPRPNIPHEQVMAEMRALIESKLNKNSAG

Nucleotide

• Length: 192 bp

>AT122795 NZ_CP038438:3448509-3448700 [Pseudomonas fluorescens]
ATGAGCGCCGAACTTTCCCTTATCGTTTCAGACTTTGAAACCCCAGAGCAGGCCGCCAGCTACGATCGCTGGTTCCGGGC
ACAGGTACAGGCCTCGATGGATGATCCGCGGCCCAACATCCCCCACGAGCAGGTGATGGCCGAGATGCGCGCCCTCATCG
AATCGAAACTCAACAAAAACAGTGCGGGTTGA

Structures

Antitoxin

• AlphaFold DB: A0A031G898