Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/- |
Location | 2776988..2778213 | Replicon | chromosome |
Accession | NZ_CP038438 | ||
Organism | Pseudomonas fluorescens strain LBUM677 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | E4T63_RS12515 | Protein ID | WP_135295602.1 |
Coordinates | 2776988..2777578 (-) | Length | 197 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | E4T63_RS12520 | Protein ID | WP_134786184.1 |
Coordinates | 2777656..2778213 (-) | Length | 186 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
E4T63_RS12490 | 2772771..2773544 | + | 774 | WP_135295599.1 | AraC family transcriptional regulator | - |
E4T63_RS12495 | 2773555..2774322 | - | 768 | WP_003224391.1 | phosphonate ABC transporter, permease protein PhnE | - |
E4T63_RS12500 | 2774319..2775146 | - | 828 | WP_135295600.1 | ABC transporter permease subunit | - |
E4T63_RS12505 | 2775140..2775937 | - | 798 | WP_135295601.1 | ATP-binding cassette domain-containing protein | - |
E4T63_RS12510 | 2775934..2776797 | - | 864 | WP_096796864.1 | putative selenate ABC transporter substrate-binding protein | - |
E4T63_RS12515 | 2776988..2777578 | - | 591 | WP_135295602.1 | HD domain-containing protein | Toxin |
E4T63_RS12520 | 2777656..2778213 | - | 558 | WP_134786184.1 | helix-turn-helix domain-containing protein | Antitoxin |
E4T63_RS12525 | 2778289..2778687 | - | 399 | WP_135295603.1 | RidA family protein | - |
E4T63_RS12530 | 2778810..2779754 | + | 945 | WP_135295604.1 | LysR family transcriptional regulator | - |
E4T63_RS12535 | 2779829..2780989 | + | 1161 | WP_135295605.1 | radical SAM protein | - |
E4T63_RS12540 | 2780971..2781858 | - | 888 | WP_135295606.1 | LysR family transcriptional regulator | - |
E4T63_RS12545 | 2781994..2783046 | + | 1053 | WP_135295607.1 | agmatine deiminase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 197 a.a. Molecular weight: 21896.71 Da Isoelectric Point: 4.5781
>T122793 WP_135295602.1 NZ_CP038438:c2777578-2776988 [Pseudomonas fluorescens]
MNLEMIKGRLEFLREAEKLKDVLRSARTSSGRTESTAEHSWRLCLMAIVFADQLAGLDLLKVLKMCVIHDLGEAINGDIP
AINQAAFPDKGEQERNDLLLLTGALDEALRSEILALWDDYENAQSAEAKAVKALDKLETLLQHNQGLNPADFDYGFNLGY
GKKYTSADPVFATLRELIDQDTRQRISDGQNSNERS
MNLEMIKGRLEFLREAEKLKDVLRSARTSSGRTESTAEHSWRLCLMAIVFADQLAGLDLLKVLKMCVIHDLGEAINGDIP
AINQAAFPDKGEQERNDLLLLTGALDEALRSEILALWDDYENAQSAEAKAVKALDKLETLLQHNQGLNPADFDYGFNLGY
GKKYTSADPVFATLRELIDQDTRQRISDGQNSNERS
Download Length: 591 bp
>T122793 NZ_CP038438:c2777578-2776988 [Pseudomonas fluorescens]
ATGAACCTCGAAATGATCAAAGGCCGCCTCGAATTCCTGCGCGAAGCAGAAAAACTCAAGGACGTGCTGCGCAGCGCGCG
CACCTCCAGCGGCCGCACCGAAAGCACCGCCGAACACAGCTGGCGCCTGTGCCTGATGGCGATTGTCTTCGCCGATCAAC
TGGCCGGCCTCGACCTGCTCAAAGTCCTGAAGATGTGCGTGATTCACGATTTGGGCGAAGCCATCAATGGCGATATTCCG
GCGATCAATCAGGCCGCGTTCCCCGACAAGGGTGAACAGGAACGCAACGACCTTCTGCTGCTGACCGGTGCGCTCGATGA
GGCGCTGCGCAGCGAAATTCTGGCGCTGTGGGACGACTACGAAAATGCTCAGTCCGCCGAAGCCAAAGCGGTCAAGGCAC
TGGATAAACTGGAGACGCTGCTGCAACACAACCAGGGGCTGAACCCGGCGGATTTCGATTACGGTTTCAATCTGGGCTAC
GGTAAGAAATACACCAGTGCCGACCCGGTCTTCGCCACCCTGCGTGAGCTGATCGACCAAGACACGCGACAGCGCATCAG
CGACGGCCAAAACAGCAACGAGCGATCTTGA
ATGAACCTCGAAATGATCAAAGGCCGCCTCGAATTCCTGCGCGAAGCAGAAAAACTCAAGGACGTGCTGCGCAGCGCGCG
CACCTCCAGCGGCCGCACCGAAAGCACCGCCGAACACAGCTGGCGCCTGTGCCTGATGGCGATTGTCTTCGCCGATCAAC
TGGCCGGCCTCGACCTGCTCAAAGTCCTGAAGATGTGCGTGATTCACGATTTGGGCGAAGCCATCAATGGCGATATTCCG
GCGATCAATCAGGCCGCGTTCCCCGACAAGGGTGAACAGGAACGCAACGACCTTCTGCTGCTGACCGGTGCGCTCGATGA
GGCGCTGCGCAGCGAAATTCTGGCGCTGTGGGACGACTACGAAAATGCTCAGTCCGCCGAAGCCAAAGCGGTCAAGGCAC
TGGATAAACTGGAGACGCTGCTGCAACACAACCAGGGGCTGAACCCGGCGGATTTCGATTACGGTTTCAATCTGGGCTAC
GGTAAGAAATACACCAGTGCCGACCCGGTCTTCGCCACCCTGCGTGAGCTGATCGACCAAGACACGCGACAGCGCATCAG
CGACGGCCAAAACAGCAACGAGCGATCTTGA
Antitoxin
Download Length: 186 a.a. Molecular weight: 20444.63 Da Isoelectric Point: 10.6088
>AT122793 WP_134786184.1 NZ_CP038438:c2778213-2777656 [Pseudomonas fluorescens]
MSDLLLKPALPGIALRRWRLLHRVKQTHAAQLFNVTQSTISRWESGVQAMEPAAQLQLERLLTARLDSAADQVLARLIGE
SQRPMHLICDLTHRLLACSPARAAEFTRPLSTLLGQSLWRFATPEIVLRESALATSGWHEVQAPPAVEFSTGSNASDLVP
IRAGRCRWTRIPLSDGSAARLVETL
MSDLLLKPALPGIALRRWRLLHRVKQTHAAQLFNVTQSTISRWESGVQAMEPAAQLQLERLLTARLDSAADQVLARLIGE
SQRPMHLICDLTHRLLACSPARAAEFTRPLSTLLGQSLWRFATPEIVLRESALATSGWHEVQAPPAVEFSTGSNASDLVP
IRAGRCRWTRIPLSDGSAARLVETL
Download Length: 558 bp
>AT122793 NZ_CP038438:c2778213-2777656 [Pseudomonas fluorescens]
ATGTCAGACCTGTTATTGAAGCCCGCCCTGCCCGGTATCGCCCTGCGACGCTGGCGCCTGCTGCATCGCGTCAAACAGAC
TCACGCGGCGCAGTTGTTCAACGTCACCCAGTCGACCATTTCCCGCTGGGAAAGCGGTGTGCAGGCGATGGAACCTGCCG
CGCAACTGCAACTGGAGCGTTTGCTGACTGCGCGCCTGGACAGCGCCGCCGATCAGGTATTGGCGCGTCTGATCGGGGAA
AGTCAGCGGCCGATGCACCTGATCTGCGACCTCACCCATCGCCTGCTGGCCTGCTCTCCTGCGCGTGCTGCCGAGTTCAC
CCGACCCTTGAGTACGTTGCTGGGACAATCGCTGTGGCGCTTCGCAACGCCGGAAATTGTGCTGAGAGAGTCGGCCCTGG
CAACCAGCGGTTGGCACGAAGTTCAGGCGCCGCCAGCCGTGGAATTCAGCACCGGCAGCAATGCCTCCGACCTCGTGCCG
ATCCGCGCCGGCCGATGCCGCTGGACGCGCATTCCACTCTCCGACGGCAGCGCCGCGCGTCTGGTGGAAACCCTCTGA
ATGTCAGACCTGTTATTGAAGCCCGCCCTGCCCGGTATCGCCCTGCGACGCTGGCGCCTGCTGCATCGCGTCAAACAGAC
TCACGCGGCGCAGTTGTTCAACGTCACCCAGTCGACCATTTCCCGCTGGGAAAGCGGTGTGCAGGCGATGGAACCTGCCG
CGCAACTGCAACTGGAGCGTTTGCTGACTGCGCGCCTGGACAGCGCCGCCGATCAGGTATTGGCGCGTCTGATCGGGGAA
AGTCAGCGGCCGATGCACCTGATCTGCGACCTCACCCATCGCCTGCTGGCCTGCTCTCCTGCGCGTGCTGCCGAGTTCAC
CCGACCCTTGAGTACGTTGCTGGGACAATCGCTGTGGCGCTTCGCAACGCCGGAAATTGTGCTGAGAGAGTCGGCCCTGG
CAACCAGCGGTTGGCACGAAGTTCAGGCGCCGCCAGCCGTGGAATTCAGCACCGGCAGCAATGCCTCCGACCTCGTGCCG
ATCCGCGCCGGCCGATGCCGCTGGACGCGCATTCCACTCTCCGACGGCAGCGCCGCGCGTCTGGTGGAAACCCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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