Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2261480..2261751 Replicon chromosome
Accession NZ_CP038428
Organism Escherichia coli O157:H7 strain 611

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2261518..2261621 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2261480..2261751 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3149_RS11655 2258637..2260076 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
E3149_RS11660 2260194..2260430 + 237 WP_001295499.1 DUF1480 family protein -
E3149_RS11665 2260535..2260726 + 192 WP_001296140.1 YebW family protein -
E3149_RS11670 2260727..2261383 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2261480..2261751 + 272 - - Antitoxin
- 2261518..2261621 - 104 - - Toxin
E3149_RS11675 2261779..2262120 - 342 WP_000976483.1 YebY family protein -
E3149_RS11680 2262133..2263005 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E3149_RS11685 2263009..2263383 - 375 WP_000168751.1 CopC domain-containing protein YobA -
E3149_RS11690 2263522..2263752 + 231 WP_000916763.1 DNA polymerase III subunit theta -
E3149_RS11695 2263854..2264510 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E3149_RS11700 2264534..2265196 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T122762 NZ_CP038428:c2261621-2261518 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT122762 NZ_CP038428:2261480-2261751 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References