Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2334936..2335207 Replicon chromosome
Accession NZ_CP038425
Organism Escherichia coli O157:H7 strain 2571

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2335066..2335169 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2334936..2335207 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3150_RS11805 2331491..2332153 - 663 WP_000944243.1 exodeoxyribonuclease X -
E3150_RS11810 2332177..2332833 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E3150_RS11815 2332935..2333165 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E3150_RS11820 2333304..2333678 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E3150_RS11825 2333682..2334554 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E3150_RS11830 2334567..2334908 + 342 WP_000976483.1 YebY family protein -
- 2334936..2335207 - 272 - - Antitoxin
- 2335066..2335169 + 104 - - Toxin
E3150_RS11835 2335304..2335960 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E3150_RS11840 2335961..2336152 - 192 WP_001296140.1 YebW family protein -
E3150_RS11845 2336257..2336493 - 237 WP_001295499.1 DUF1480 family protein -
E3150_RS11850 2336611..2338050 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T122729 NZ_CP038425:2335066-2335169 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT122729 NZ_CP038425:c2335207-2334936 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References