Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2285886..2286157 Replicon chromosome
Accession NZ_CP038421
Organism Escherichia coli O157:H7 strain 7636

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2286016..2286119 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2285886..2286157 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3152_RS11430 2282441..2283103 - 663 WP_000944243.1 exodeoxyribonuclease X -
E3152_RS11435 2283127..2283783 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E3152_RS11440 2283885..2284115 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E3152_RS11445 2284254..2284628 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E3152_RS11450 2284632..2285504 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E3152_RS11455 2285517..2285858 + 342 WP_000976483.1 YebY family protein -
- 2285886..2286157 - 272 - - Antitoxin
- 2286016..2286119 + 104 - - Toxin
E3152_RS11460 2286254..2286910 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E3152_RS11465 2286911..2287102 - 192 WP_001296140.1 YebW family protein -
E3152_RS11470 2287207..2287443 - 237 WP_001295499.1 DUF1480 family protein -
E3152_RS11475 2287561..2289000 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T122655 NZ_CP038421:2286016-2286119 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT122655 NZ_CP038421:c2286157-2285886 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References