Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2246612..2246883 Replicon chromosome
Accession NZ_CP038414
Organism Escherichia coli O157:H7 strain 17B6-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2246742..2246845 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2246612..2246883 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4U86_RS11225 2243167..2243829 - 663 WP_000944243.1 exodeoxyribonuclease X -
E4U86_RS11230 2243853..2244509 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E4U86_RS11235 2244611..2244841 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E4U86_RS11240 2244980..2245354 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E4U86_RS11245 2245358..2246230 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E4U86_RS11250 2246243..2246584 + 342 WP_000976483.1 YebY family protein -
- 2246612..2246883 - 272 - - Antitoxin
- 2246742..2246845 + 104 - - Toxin
E4U86_RS11255 2246980..2247636 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E4U86_RS11260 2247637..2247828 - 192 WP_001296140.1 YebW family protein -
E4U86_RS11265 2247933..2248169 - 237 WP_001295499.1 DUF1480 family protein -
E4U86_RS11270 2248287..2249726 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T122539 NZ_CP038414:2246742-2246845 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT122539 NZ_CP038414:c2246883-2246612 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References