Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2194170..2194441 Replicon chromosome
Accession NZ_CP038405
Organism Escherichia coli O157:H7 strain ATCC 35150

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2194300..2194403 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2194170..2194441 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3153_RS10835 2190725..2191387 - 663 WP_000944243.1 exodeoxyribonuclease X -
E3153_RS10840 2191411..2192067 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E3153_RS10845 2192169..2192399 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E3153_RS10850 2192538..2192912 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E3153_RS10855 2192916..2193788 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E3153_RS10860 2193801..2194142 + 342 WP_000976483.1 YebY family protein -
- 2194170..2194441 - 272 - - Antitoxin
- 2194300..2194403 + 104 - - Toxin
E3153_RS10865 2194538..2195194 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E3153_RS10870 2195195..2195386 - 192 WP_001296140.1 YebW family protein -
E3153_RS10875 2195491..2195727 - 237 WP_001295499.1 DUF1480 family protein -
E3153_RS10880 2195845..2197284 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T122435 NZ_CP038405:2194300-2194403 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT122435 NZ_CP038405:c2194441-2194170 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References