Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2196675..2196946 Replicon chromosome
Accession NZ_CP038386
Organism Escherichia coli O157:H7 strain DEC5D

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2196805..2196908 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2196675..2196946 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3157_RS10510 2193230..2193892 - 663 WP_000944256.1 exodeoxyribonuclease X -
E3157_RS10515 2193916..2194572 - 657 WP_000011661.1 carbon-nitrogen hydrolase family protein -
E3157_RS10520 2194674..2194904 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E3157_RS10525 2195043..2195417 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E3157_RS10530 2195421..2196293 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E3157_RS10535 2196306..2196647 + 342 WP_000976483.1 YebY family protein -
- 2196675..2196946 - 272 - - Antitoxin
- 2196805..2196908 + 104 - - Toxin
E3157_RS10540 2197043..2197699 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E3157_RS10545 2197700..2197891 - 192 WP_001296140.1 YebW family protein -
E3157_RS10550 2197996..2198232 - 237 WP_001359800.1 DUF1480 family protein -
E3157_RS10555 2198350..2199789 - 1440 WP_001419087.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T122266 NZ_CP038386:2196805-2196908 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT122266 NZ_CP038386:c2196946-2196675 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References