Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3086946..3087180 | Replicon | chromosome |
| Accession | NZ_CP038383 | ||
| Organism | Escherichia coli O157:H7 strain DEC5E | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3086947..3087050 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3086946..3087180 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E3158_RS15135 | 3083894..3084946 | + | 1053 | WP_001004417.1 | recombinase RecT | - |
| E3158_RS15140 | 3085010..3085204 | + | 195 | WP_010989194.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| E3158_RS15145 | 3085197..3085385 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 3085203..3085381 | - | 179 | NuclAT_0 | - | - |
| - | 3085203..3085381 | - | 179 | NuclAT_0 | - | - |
| - | 3085203..3085381 | - | 179 | NuclAT_0 | - | - |
| - | 3085203..3085381 | - | 179 | NuclAT_0 | - | - |
| E3158_RS15150 | 3085492..3085773 | + | 282 | WP_001311878.1 | excisionase | - |
| E3158_RS15155 | 3085739..3086815 | + | 1077 | WP_001189084.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 3086946..3087180 | + | 235 | - | - | Antitoxin |
| - | 3086947..3087050 | - | 104 | - | - | Toxin |
| E3158_RS15160 | 3087208..3087549 | - | 342 | WP_000976483.1 | YebY family protein | - |
| E3158_RS15165 | 3087562..3088434 | - | 873 | WP_000879314.1 | copper homeostasis membrane protein CopD | - |
| E3158_RS15170 | 3088438..3088812 | - | 375 | WP_000168751.1 | CopC domain-containing protein YobA | - |
| E3158_RS15175 | 3088951..3089181 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| E3158_RS15180 | 3089283..3089939 | + | 657 | WP_000011661.1 | carbon-nitrogen hydrolase family protein | - |
| E3158_RS15185 | 3089963..3090625 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 3036639..3092682 | 56043 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T122233 NZ_CP038383:c3087050-3086947 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT122233 NZ_CP038383:3086946-3087180 [Escherichia coli O157:H7]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
