Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3238415..3238686 Replicon chromosome
Accession NZ_CP038376
Organism Escherichia coli O157:H7 strain F1273

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3238453..3238556 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3238415..3238686 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3159_RS15995 3235572..3237011 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
E3159_RS16000 3237129..3237365 + 237 WP_001295499.1 DUF1480 family protein -
E3159_RS16005 3237470..3237661 + 192 WP_001296140.1 YebW family protein -
E3159_RS16010 3237662..3238318 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 3238415..3238686 + 272 - - Antitoxin
- 3238453..3238556 - 104 - - Toxin
E3159_RS16015 3238714..3239055 - 342 WP_000976483.1 YebY family protein -
E3159_RS16020 3239068..3239940 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E3159_RS16025 3239944..3240318 - 375 WP_000168751.1 CopC domain-containing protein YobA -
E3159_RS16030 3240457..3240687 + 231 WP_000916763.1 DNA polymerase III subunit theta -
E3159_RS16035 3240789..3241445 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E3159_RS16040 3241469..3242131 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T122169 NZ_CP038376:c3238556-3238453 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT122169 NZ_CP038376:3238415-3238686 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References