Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3188467..3188738 Replicon chromosome
Accession NZ_CP038374
Organism Escherichia coli O157:H7 strain F3113

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3188505..3188608 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3188467..3188738 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3160_RS15520 3185624..3187063 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
E3160_RS15525 3187181..3187417 + 237 WP_001295499.1 DUF1480 family protein -
E3160_RS15530 3187522..3187713 + 192 WP_001296140.1 YebW family protein -
E3160_RS15535 3187714..3188370 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 3188467..3188738 + 272 - - Antitoxin
- 3188505..3188608 - 104 - - Toxin
E3160_RS15540 3188766..3189107 - 342 WP_000976483.1 YebY family protein -
E3160_RS15545 3189120..3189992 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E3160_RS15550 3189996..3190370 - 375 WP_000168751.1 CopC domain-containing protein YobA -
E3160_RS15555 3190509..3190739 + 231 WP_000916763.1 DNA polymerase III subunit theta -
E3160_RS15560 3190841..3191497 + 657 WP_000011645.1 carbon-nitrogen hydrolase family protein -
E3160_RS15565 3191521..3192183 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T122128 NZ_CP038374:c3188608-3188505 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT122128 NZ_CP038374:3188467-3188738 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGTAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References