Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2334278..2334549 Replicon chromosome
Accession NZ_CP038369
Organism Escherichia coli O157:H7 strain F6321

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2334408..2334511 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2334278..2334549 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3162_RS11805 2330833..2331495 - 663 WP_000944243.1 exodeoxyribonuclease X -
E3162_RS11810 2331519..2332175 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E3162_RS11815 2332277..2332507 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E3162_RS11820 2332646..2333020 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E3162_RS11825 2333024..2333896 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E3162_RS11830 2333909..2334250 + 342 WP_000976483.1 YebY family protein -
- 2334278..2334549 - 272 - - Antitoxin
- 2334408..2334511 + 104 - - Toxin
E3162_RS11835 2334646..2335302 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E3162_RS11840 2335303..2335494 - 192 WP_001296140.1 YebW family protein -
E3162_RS11845 2335599..2335835 - 237 WP_001295499.1 DUF1480 family protein -
E3162_RS11850 2335953..2337392 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T122057 NZ_CP038369:2334408-2334511 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT122057 NZ_CP038369:c2334549-2334278 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References