Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2264574..2264845 Replicon chromosome
Accession NZ_CP038360
Organism Escherichia coli O157:H7 strain F7386

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2264704..2264807 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2264574..2264845 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4U67_RS11315 2261129..2261791 - 663 WP_000944244.1 exodeoxyribonuclease X -
E4U67_RS11320 2261815..2262471 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E4U67_RS11325 2262573..2262803 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E4U67_RS11330 2262942..2263316 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E4U67_RS11335 2263320..2264192 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E4U67_RS11340 2264205..2264546 + 342 WP_000976483.1 YebY family protein -
- 2264574..2264845 - 272 - - Antitoxin
- 2264704..2264807 + 104 - - Toxin
E4U67_RS11345 2264942..2265598 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E4U67_RS11350 2265599..2265790 - 192 WP_001296140.1 YebW family protein -
E4U67_RS11355 2265895..2266131 - 237 WP_001295499.1 DUF1480 family protein -
E4U67_RS11360 2266249..2267688 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T121947 NZ_CP038360:2264704-2264807 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT121947 NZ_CP038360:c2264845-2264574 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References