Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2231543..2231814 Replicon chromosome
Accession NZ_CP038344
Organism Escherichia coli O157:H7 strain Gim1-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2231673..2231776 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2231543..2231814 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4U63_RS11040 2228098..2228760 - 663 WP_000944243.1 exodeoxyribonuclease X -
E4U63_RS11045 2228784..2229440 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E4U63_RS11050 2229542..2229772 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E4U63_RS11055 2229911..2230285 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E4U63_RS11060 2230289..2231161 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E4U63_RS11065 2231174..2231515 + 342 WP_000976483.1 YebY family protein -
- 2231543..2231814 - 272 - - Antitoxin
- 2231673..2231776 + 104 - - Toxin
E4U63_RS11070 2231911..2232567 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E4U63_RS11075 2232568..2232759 - 192 WP_001296140.1 YebW family protein -
E4U63_RS11080 2232864..2233100 - 237 WP_001295499.1 DUF1480 family protein -
E4U63_RS11085 2233218..2234657 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T121695 NZ_CP038344:2231673-2231776 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT121695 NZ_CP038344:c2231814-2231543 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References