Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2316049..2316320 Replicon chromosome
Accession NZ_CP038339
Organism Escherichia coli O157:H7 strain H6437

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2316179..2316282 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2316049..2316320 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3164_RS11640 2312604..2313266 - 663 WP_000944244.1 exodeoxyribonuclease X -
E3164_RS11645 2313290..2313946 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E3164_RS11650 2314048..2314278 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E3164_RS11655 2314417..2314791 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E3164_RS11660 2314795..2315667 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E3164_RS11665 2315680..2316021 + 342 WP_000976483.1 YebY family protein -
- 2316049..2316320 - 272 - - Antitoxin
- 2316179..2316282 + 104 - - Toxin
E3164_RS11670 2316417..2317073 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E3164_RS11675 2317074..2317265 - 192 WP_001296140.1 YebW family protein -
E3164_RS11680 2317370..2317606 - 237 WP_001295499.1 DUF1480 family protein -
E3164_RS11685 2317724..2319163 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T121628 NZ_CP038339:2316179-2316282 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT121628 NZ_CP038339:c2316320-2316049 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References