Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2271233..2271504 Replicon chromosome
Accession NZ_CP038336
Organism Escherichia coli O157:H7 strain LSU61

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2271363..2271466 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2271233..2271504 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3165_RS11150 2267788..2268450 - 663 WP_000944256.1 exodeoxyribonuclease X -
E3165_RS11155 2268474..2269130 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E3165_RS11160 2269232..2269462 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E3165_RS11165 2269601..2269975 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E3165_RS11170 2269979..2270851 + 873 WP_000879312.1 copper homeostasis membrane protein CopD -
E3165_RS11175 2270864..2271205 + 342 WP_000976483.1 YebY family protein -
- 2271233..2271504 - 272 - - Antitoxin
- 2271363..2271466 + 104 - - Toxin
E3165_RS11180 2271601..2272257 + 657 Protein_2186 protein-serine/threonine phosphatase -
E3165_RS11185 2272258..2272449 - 192 WP_001296140.1 YebW family protein -
E3165_RS11190 2272554..2272790 - 237 WP_001295499.1 DUF1480 family protein -
E3165_RS11195 2272908..2274347 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2265731..2277061 11330


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T121585 NZ_CP038336:2271363-2271466 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT121585 NZ_CP038336:c2271504-2271233 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References