Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3197324..3197595 Replicon chromosome
Accession NZ_CP038333
Organism Escherichia coli O157:H7 strain N8B7-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3197362..3197465 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3197324..3197595 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4U68_RS16410 3194481..3195920 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
E4U68_RS16415 3196038..3196274 + 237 WP_001295499.1 DUF1480 family protein -
E4U68_RS16420 3196379..3196570 + 192 WP_001296140.1 YebW family protein -
E4U68_RS16425 3196571..3197227 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 3197324..3197595 + 272 - - Antitoxin
- 3197362..3197465 - 104 - - Toxin
E4U68_RS16430 3197623..3197964 - 342 WP_000976483.1 YebY family protein -
E4U68_RS16435 3197977..3198849 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E4U68_RS16440 3198853..3199227 - 375 WP_000168751.1 CopC domain-containing protein YobA -
E4U68_RS16445 3199366..3199596 + 231 WP_000916763.1 DNA polymerase III subunit theta -
E4U68_RS16450 3199698..3200354 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E4U68_RS16455 3200378..3201040 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T121555 NZ_CP038333:c3197465-3197362 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT121555 NZ_CP038333:3197324-3197595 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References