Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2192621..2192892 Replicon chromosome
Accession NZ_CP038313
Organism Escherichia coli O157:H7 strain OK1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2192751..2192854 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2192621..2192892 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3173_RS10790 2189176..2189838 - 663 WP_000944243.1 exodeoxyribonuclease X -
E3173_RS10795 2189862..2190518 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E3173_RS10800 2190620..2190850 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E3173_RS10805 2190989..2191363 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E3173_RS10810 2191367..2192239 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E3173_RS10815 2192252..2192593 + 342 WP_000976483.1 YebY family protein -
- 2192621..2192892 - 272 - - Antitoxin
- 2192751..2192854 + 104 - - Toxin
E3173_RS10820 2192989..2193645 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E3173_RS10825 2193646..2193837 - 192 WP_001296140.1 YebW family protein -
E3173_RS10830 2193942..2194178 - 237 WP_001295499.1 DUF1480 family protein -
E3173_RS10835 2194296..2195735 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T121344 NZ_CP038313:2192751-2192854 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT121344 NZ_CP038313:c2192892-2192621 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References