Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2342604..2342875 Replicon chromosome
Accession NZ_CP038309
Organism Escherichia coli O157:H7 strain Show KS 470-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2342734..2342837 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2342604..2342875 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4U84_RS11900 2339159..2339821 - 663 WP_000944243.1 exodeoxyribonuclease X -
E4U84_RS11905 2339845..2340501 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E4U84_RS11910 2340603..2340833 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E4U84_RS11915 2340972..2341346 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E4U84_RS11920 2341350..2342222 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E4U84_RS11925 2342235..2342576 + 342 WP_000976483.1 YebY family protein -
- 2342604..2342875 - 272 - - Antitoxin
- 2342734..2342837 + 104 - - Toxin
E4U84_RS11930 2342972..2343628 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E4U84_RS11935 2343629..2343820 - 192 WP_001296140.1 YebW family protein -
E4U84_RS11940 2343925..2344161 - 237 WP_001295499.1 DUF1480 family protein -
E4U84_RS11945 2344279..2345718 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T121301 NZ_CP038309:2342734-2342837 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT121301 NZ_CP038309:c2342875-2342604 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References