Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2286182..2286453 Replicon chromosome
Accession NZ_CP038305
Organism Escherichia coli O157:H7 strain SS NE 1040-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2286312..2286415 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2286182..2286453 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4U78_RS11495 2282737..2283399 - 663 WP_000944243.1 exodeoxyribonuclease X -
E4U78_RS11500 2283423..2284079 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E4U78_RS11505 2284181..2284411 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E4U78_RS11510 2284550..2284924 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E4U78_RS11515 2284928..2285800 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E4U78_RS11520 2285813..2286154 + 342 WP_000976483.1 YebY family protein -
- 2286182..2286453 - 272 - - Antitoxin
- 2286312..2286415 + 104 - - Toxin
E4U78_RS11525 2286550..2287206 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E4U78_RS11530 2287207..2287398 - 192 WP_001296140.1 YebW family protein -
E4U78_RS11535 2287503..2287739 - 237 WP_001295499.1 DUF1480 family protein -
E4U78_RS11540 2287857..2289296 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T121260 NZ_CP038305:2286312-2286415 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT121260 NZ_CP038305:c2286453-2286182 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References