Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2243535..2243806 Replicon chromosome
Accession NZ_CP038292
Organism Escherichia coli O157:H7 strain TB21-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2243665..2243768 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2243535..2243806 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4U65_RS11170 2240090..2240752 - 663 WP_000944243.1 exodeoxyribonuclease X -
E4U65_RS11175 2240776..2241432 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E4U65_RS11180 2241534..2241764 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E4U65_RS11185 2241903..2242277 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E4U65_RS11190 2242281..2243153 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E4U65_RS11195 2243166..2243507 + 342 WP_000976483.1 YebY family protein -
- 2243535..2243806 - 272 - - Antitoxin
- 2243665..2243768 + 104 - - Toxin
E4U65_RS11200 2243903..2244559 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E4U65_RS11205 2244560..2244751 - 192 WP_001296140.1 YebW family protein -
E4U65_RS11210 2244856..2245092 - 237 WP_001295499.1 DUF1480 family protein -
E4U65_RS11215 2245210..2246649 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T121120 NZ_CP038292:2243665-2243768 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT121120 NZ_CP038292:c2243806-2243535 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References