Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2327014..2327285 Replicon chromosome
Accession NZ_CP038282
Organism Escherichia coli O157:H7 strain F8492

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2327144..2327247 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2327014..2327285 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4T53_RS11795 2323569..2324231 - 663 WP_000944243.1 exodeoxyribonuclease X -
E4T53_RS11800 2324255..2324911 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E4T53_RS11805 2325013..2325243 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E4T53_RS11810 2325382..2325756 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E4T53_RS11815 2325760..2326632 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E4T53_RS11820 2326645..2326986 + 342 WP_000976483.1 YebY family protein -
- 2327014..2327285 - 272 - - Antitoxin
- 2327144..2327247 + 104 - - Toxin
E4T53_RS11825 2327382..2328038 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E4T53_RS11830 2328039..2328230 - 192 WP_001296140.1 YebW family protein -
E4T53_RS11835 2328335..2328571 - 237 WP_001295499.1 DUF1480 family protein -
E4T53_RS11840 2328689..2330128 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T120961 NZ_CP038282:2327144-2327247 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT120961 NZ_CP038282:c2327285-2327014 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References