Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ(toxin)
Location 826504..826983 Replicon chromosome
Accession NZ_CP038271
Organism Legionella geestiana strain 1308

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag E4T54_RS03565 Protein ID WP_172607330.1
Coordinates 826804..826983 (+) Length 60 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag E4T54_RS03560 Protein ID WP_081776765.1
Coordinates 826504..826701 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4T54_RS03540 822209..822448 - 240 WP_051550939.1 hypothetical protein -
E4T54_RS03545 822463..823338 - 876 WP_028386644.1 4-hydroxy-tetrahydrodipicolinate synthase -
E4T54_RS03550 823569..823748 + 180 WP_162150892.1 hypothetical protein -
E4T54_RS03555 823849..826368 + 2520 WP_028386642.1 PD-(D/E)XK nuclease family protein -
E4T54_RS03560 826504..826701 + 198 WP_081776765.1 addiction module antitoxin Antitoxin
E4T54_RS03565 826804..826983 + 180 WP_172607330.1 type II toxin-antitoxin system YafQ family toxin Toxin
E4T54_RS03570 827285..828250 - 966 WP_028386640.1 EF-P lysine aminoacylase GenX -
E4T54_RS03575 828250..828585 - 336 WP_028386639.1 SUF system Fe-S cluster assembly protein -
E4T54_RS03580 828589..829032 - 444 WP_028386638.1 SUF system NifU family Fe-S cluster assembly protein -
E4T54_RS03585 829029..830264 - 1236 WP_035902549.1 cysteine desulfurase -
E4T54_RS03590 830264..831520 - 1257 WP_028386636.1 Fe-S cluster assembly protein SufD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-58)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 7020.01 Da        Isoelectric Point: 6.3181

>T120925 WP_172607330.1 NZ_CP038271:826804-826983 [Legionella geestiana]
MTLLIDEKNLPAEYKDHPLKGNWAHHRDSHIEPDWLLIYKIDGKDIYFVRTGTHADLFM

Download         Length: 180 bp

>T120925 NZ_CP038271:826804-826983 [Legionella geestiana]
ATGACACTTTTAATCGATGAAAAAAACCTGCCCGCTGAATATAAAGACCATCCTTTGAAAGGCAATTGGGCGCACCATCG
AGACAGCCATATTGAGCCTGACTGGTTACTTATCTATAAAATAGACGGAAAAGATATTTATTTTGTGCGAACAGGTACCC
ATGCCGACCTCTTCATGTAA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7163.28 Da        Isoelectric Point: 7.2023

>AT120925 WP_081776765.1 NZ_CP038271:826504-826701 [Legionella geestiana]
MHDKFMAAVAAVHTPAAQVVRQLMRKFIAQQEIPNDATIAAMQSADKGEGIRFKSADEFFKDLGI

Download         Length: 198 bp

>AT120925 NZ_CP038271:826504-826701 [Legionella geestiana]
CTGCACGATAAGTTTATGGCAGCAGTCGCAGCTGTTCATACACCGGCCGCACAGGTCGTAAGACAACTGATGCGAAAATT
TATCGCTCAACAGGAAATTCCTAACGATGCAACGATTGCTGCGATGCAATCTGCCGATAAAGGTGAAGGAATACGGTTTA
AAAGTGCAGACGAATTTTTTAAAGACTTAGGGATTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References