120894

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 861866..862343 Replicon chromosome
Accession NZ_CP038268
Organism Staphylococcus aureus strain O55 isolate B118

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag SaO55_RS04355 Protein ID WP_000052076.1
Coordinates 861866..862054 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag SaO55_RS04360 Protein ID WP_001059690.1
Coordinates 862083..862343 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SaO55_RS04325 857855..858376 + 522 WP_000824476.1 hypothetical protein -
SaO55_RS04330 858717..859403 + 687 WP_000141556.1 thermonuclease family protein -
SaO55_RS04335 859760..859960 + 201 WP_001059082.1 cold-shock protein -
SaO55_RS04340 860457..860675 - 219 WP_000005883.1 hypothetical protein -
SaO55_RS04345 860737..861021 - 285 WP_001004401.1 hypothetical protein -
SaO55_RS04350 861109..861678 - 570 WP_001106648.1 hypothetical protein -
SaO55_RS04355 861866..862054 - 189 WP_000052076.1 hypothetical protein Toxin
SaO55_RS04360 862083..862343 - 261 WP_001059690.1 hypothetical protein Antitoxin
SaO55_RS04365 862684..862887 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
SaO55_RS04370 862884..863120 - 237 WP_000368687.1 hypothetical protein -
SaO55_RS04375 863345..863926 + 582 WP_001140696.1 phosphoglycerate mutase family protein -
SaO55_RS04380 863999..864616 - 618 WP_000255565.1 LysE/ArgO family amino acid transporter -
SaO55_RS04385 864772..865266 - 495 WP_000569881.1 GNAT family N-acetyltransferase -
SaO55_RS04390 865665..866087 - 423 WP_000974462.1 organic hydroperoxide resistance protein -
SaO55_RS04395 866235..866951 + 717 WP_000150032.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 856500..886281 29781


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T120894 WP_000052076.1 NZ_CP038268:c862054-861866 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

>T120894 NZ_CP038268:c862054-861866 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTTTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAATCCTATTTAAGTTTCACTGTCATTCTCTATATATTCGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT120894 WP_001059690.1 NZ_CP038268:c862343-862083 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp

>AT120894 NZ_CP038268:c862343-862083 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References