Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3447211..3447842 Replicon chromosome
Accession NZ_CP038255
Organism Terasakiella sp. SH-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag E4K71_RS16215 Protein ID WP_135081333.1
Coordinates 3447441..3447842 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag E4K71_RS16210 Protein ID WP_135081331.1
Coordinates 3447211..3447441 (+) Length 77 a.a.

Genomic Context

E4K71_RS16190E4K71_RS16195E4K71_RS16200E4K71_RS16205E4K71_RS16210E4K71_RS16215E4K71_RS16220E4K71_RS16225E4K71_RS16230E4K71_RS16235E4K71_RS16240E4K71_RS16245E4K71_RS16250
Location: 3442834..3443376 (543 bp)
Type: Others
Protein ID: WP_135081325.1
Location: 3443486..3445309 (1824 bp)
Type: Others
Protein ID: WP_135081326.1
Location: 3445442..3446332 (891 bp)
Type: Others
Protein ID: WP_135081327.1
Location: 3446372..3447142 (771 bp)
Type: Others
Protein ID: WP_135081329.1
Location: 3447211..3447441 (231 bp)
Type: Antitoxin
Protein ID: WP_135081331.1
Location: 3447441..3447842 (402 bp)
Type: Toxin
Protein ID: WP_135081333.1
Location: 3447843..3449267 (1425 bp)
Type: Others
Protein ID: WP_135081335.1
Location: 3449264..3449941 (678 bp)
Type: Others
Protein ID: WP_135081337.1
Location: 3449934..3450518 (585 bp)
Type: Others
Protein ID: WP_135081339.1
Location: 3450543..3450905 (363 bp)
Type: Others
Protein ID: WP_135081341.1
Location: 3450911..3451837 (927 bp)
Type: Others
Protein ID: WP_135081342.1
Location: 3451842..3452258 (417 bp)
Type: Others
Protein ID: WP_167730640.1
Location: 3452252..3452671 (420 bp)
Type: Others
Protein ID: WP_135081346.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
E4K71_RS161903442834..3443376+543WP_135081325.1DUF4405 domain-containing protein-
E4K71_RS161953443486..3445309+1824WP_135081326.1translational GTPase TypA-
E4K71_RS162003445442..3446332+891WP_135081327.1DMT family transporter-
E4K71_RS162053446372..3447142+771WP_135081329.1(Fe-S)-binding protein-
E4K71_RS162103447211..3447441+231WP_135081331.1antitoxinAntitoxin
E4K71_RS162153447441..3447842+402WP_135081333.1tRNA(fMet)-specific endonuclease VapCToxin
E4K71_RS162203447843..3449267+1425WP_135081335.1iron-sulfur cluster-binding protein-
E4K71_RS162253449264..3449941+678WP_135081337.1lactate utilization protein-
E4K71_RS162303449934..3450518+585WP_135081339.1Smr/MutS family protein-
E4K71_RS162353450543..3450905+363WP_135081341.1helix-turn-helix domain-containing protein-
E4K71_RS162403450911..3451837+927WP_135081342.1hypothetical protein-
E4K71_RS162453451842..3452258+417WP_167730640.1GtrA family protein-
E4K71_RS162503452252..3452671-420WP_135081346.1group III truncated hemoglobin-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

SpoVT-AbrB domain

(7-33)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15190.48 Da        Isoelectric Point: 6.8643

>T120872 WP_135081333.1 NZ_CP038255:3447441-3447842 [Terasakiella sp. SH-1]
MLRYMLDTNICIFVIKNRPEHMRAVFNEKSHSMCVSAITVAELIYGAEKSVQKEKNLKVVEGFLSRLETLDFDEEAANHY
GEIRAALEKKGLPIGPYDLMLAGHSRSRGLVMVTNNTREFSRVDGLRLEDWSQ

Download         Length: 402 bp

>T120872 NZ_CP038255:3447441-3447842 [Terasakiella sp. SH-1]
ATGTTACGCTATATGCTGGATACGAACATTTGTATTTTTGTGATTAAAAACCGCCCTGAACATATGCGCGCTGTTTTTAA
TGAAAAATCTCATTCTATGTGTGTATCCGCCATTACTGTTGCTGAATTGATCTATGGTGCTGAAAAATCAGTACAAAAAG
AGAAAAACCTGAAAGTGGTTGAGGGTTTTTTGTCCCGCCTTGAAACTCTTGATTTTGATGAGGAAGCGGCAAACCATTAC
GGCGAGATTCGTGCTGCGCTTGAAAAAAAAGGTTTACCTATCGGGCCTTATGATTTGATGTTGGCAGGACATTCGCGTTC
ACGTGGTTTGGTGATGGTGACAAATAATACACGGGAATTTTCCCGTGTTGATGGGTTACGTTTAGAGGATTGGAGTCAAT
AA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8704.87 Da        Isoelectric Point: 4.5535

>AT120872 WP_135081331.1 NZ_CP038255:3447211-3447441 [Terasakiella sp. SH-1]
MTQSSVFKNNQTQAVRIPKAVALPEHIKKVDVIKQGNARLIVPSDCLWDSFFDGEQPSDDFMVERSEPEMQVREEL

Download         Length: 231 bp

>AT120872 NZ_CP038255:3447211-3447441 [Terasakiella sp. SH-1]
ATGACACAGAGCAGTGTATTTAAGAATAATCAAACACAAGCTGTTCGTATCCCTAAGGCTGTTGCATTACCGGAACATAT
AAAAAAGGTGGATGTCATCAAACAGGGGAATGCACGCCTTATTGTGCCCAGTGATTGTCTTTGGGACAGTTTTTTCGATG
GAGAGCAGCCAAGCGATGATTTTATGGTTGAGCGCTCTGAACCTGAAATGCAGGTGCGTGAGGAACTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References