Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelB-YoeB
Location 1609522..1610030 Replicon chromosome
Accession NZ_CP038241
Organism Allofrancisella inopinata strain SYSU YG23

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E4K63_RS07435 Protein ID WP_133942547.1
Coordinates 1609522..1609779 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag E4K63_RS07440 Protein ID WP_133942546.1
Coordinates 1609776..1610030 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4K63_RS07415 1605560..1605796 + 237 WP_133942550.1 hypothetical protein -
E4K63_RS07420 1605799..1606881 - 1083 WP_179965672.1 transposase -
E4K63_RS07425 1606923..1607741 + 819 WP_133942549.1 2-hydroxyacid dehydrogenase -
E4K63_RS07430 1607997..1609289 + 1293 WP_133942548.1 MFS transporter -
E4K63_RS07435 1609522..1609779 + 258 WP_133942547.1 type II toxin-antitoxin system prevent-host-death family antitoxin Toxin
E4K63_RS07440 1609776..1610030 + 255 WP_133942546.1 Txe/YoeB family addiction module toxin Antitoxin
E4K63_RS07445 1610324..1610746 + 423 WP_035720378.1 rhodanese-like domain-containing protein -
E4K63_RS07450 1610774..1611223 + 450 WP_133942545.1 protein-export chaperone SecB -
E4K63_RS07455 1611236..1612288 + 1053 WP_133942544.1 recombinase RecA -
E4K63_RS07460 1612275..1612730 + 456 WP_133942543.1 recombination regulator RecX -
E4K63_RS07465 1612826..1613281 + 456 WP_133942542.1 single-stranded DNA-binding protein -
E4K63_RS07470 1613362..1613811 - 450 WP_133942541.1 hypothetical protein -
E4K63_RS07475 1613902..1614570 - 669 WP_179965703.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)

Antitoxin

Toxin YoeB

(1-84)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9740.88 Da        Isoelectric Point: 4.6104

>T120845 WP_133942547.1 NZ_CP038241:1609522-1609779 [Allofrancisella inopinata]
MRTLNYTSFRNELASSMDSVIEDHQPIVVTRGSEKKAVVVMSLDDFKSYQETAHLMSSINNYNRLDQSIKELESGNSIQK
ELIEE

Download         Length: 258 bp

>T120845 NZ_CP038241:1609522-1609779 [Allofrancisella inopinata]
ATGAGAACTTTAAACTATACCTCATTCAGAAATGAGCTGGCATCATCGATGGATAGCGTCATTGAGGATCATCAACCTAT
CGTTGTTACTAGAGGCTCCGAAAAAAAAGCTGTTGTTGTGATGTCTTTAGATGATTTTAAATCGTATCAAGAAACGGCGC
ATTTGATGTCTAGCATAAATAACTATAATAGACTTGATCAATCTATAAAAGAACTTGAGTCTGGTAATTCAATACAAAAA
GAGCTTATTGAAGAATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 10414.91 Da        Isoelectric Point: 9.9709

>AT120845 WP_133942546.1 NZ_CP038241:1609776-1610030 [Allofrancisella inopinata]
MILSWSTNAWEDYLYWQANDKKKLKRINQLIKDIKRNYFEGLGGPEPLKHNWTGYWSRRIDREHRLVYKIQDNNILIAQC
RYHY

Download         Length: 255 bp

>AT120845 NZ_CP038241:1609776-1610030 [Allofrancisella inopinata]
ATGATATTATCTTGGTCAACTAACGCTTGGGAAGATTATCTTTATTGGCAAGCAAATGATAAGAAAAAGTTAAAGCGTAT
AAATCAGTTAATCAAAGATATTAAAAGAAATTATTTTGAAGGCTTGGGTGGTCCAGAACCACTTAAACACAATTGGACTG
GATACTGGTCAAGAAGGATCGATAGAGAACATCGCTTAGTTTACAAAATTCAGGATAATAATATTCTCATTGCTCAATGC
AGATATCACTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References