Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 6007465..6009191 Replicon chromosome
Accession NZ_CP038207
Organism Pseudomonas sp. S150

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag E3Z29_RS27920 Protein ID WP_096796317.1
Coordinates 6007465..6008109 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag E3Z29_RS27925 Protein ID WP_134787420.1
Coordinates 6008106..6009191 (+) Length 362 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3Z29_RS27895 6002868..6003680 + 813 WP_027612913.1 zinc-dependent peptidase -
E3Z29_RS27900 6003793..6004320 + 528 WP_008052339.1 inorganic diphosphatase -
E3Z29_RS27905 6004544..6005290 + 747 WP_027612915.1 helix-turn-helix transcriptional regulator -
E3Z29_RS27910 6005799..6006719 + 921 WP_098965795.1 restriction endonuclease -
E3Z29_RS27915 6006905..6007468 + 564 WP_134787419.1 DUF4433 domain-containing protein -
E3Z29_RS27920 6007465..6008109 + 645 WP_096796317.1 DUF4433 domain-containing protein Toxin
E3Z29_RS27925 6008106..6009191 + 1086 WP_134787420.1 macro domain-containing protein Antitoxin
E3Z29_RS27930 6009365..6009925 + 561 WP_134787421.1 hypothetical protein -
E3Z29_RS27935 6009941..6010375 + 435 WP_134787422.1 hypothetical protein -
E3Z29_RS27940 6010399..6011211 - 813 WP_098965801.1 DUF2135 domain-containing protein -
E3Z29_RS27945 6011215..6012834 - 1620 WP_134787423.1 DUF2300 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24904.56 Da        Isoelectric Point: 6.9118

>T120811 WP_096796317.1 NZ_CP038207:6007465-6008109 [Pseudomonas sp. S150]
MIYTNLNPEKALIWRIVHRDNLPWILDNGLHCANSEAKAPQYVNIGNVDLIDKRRFRQVPIAPEGVLADYVPFYFTPFSV
MMQNIHSGWSVQQRGNDEIVILVSSLYRVEELGLPFVFTNAHAYPSWTNYYSDLANLDQIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHQHLPITGLLGIMCHTDAMKVRIEADVAVRGLTLPVHARPKWYFQ

Download         Length: 645 bp

>T120811 NZ_CP038207:6007465-6008109 [Pseudomonas sp. S150]
ATGATCTATACCAACCTGAATCCAGAGAAAGCTCTGATTTGGCGTATCGTCCATCGCGATAACCTGCCCTGGATTCTGGA
CAACGGTCTGCATTGCGCAAACTCGGAAGCAAAGGCACCTCAGTACGTGAATATCGGCAACGTCGACTTGATCGACAAAC
GCCGTTTCCGTCAGGTGCCTATCGCACCCGAAGGCGTACTGGCCGACTACGTGCCCTTCTATTTCACACCCTTCTCGGTG
ATGATGCAGAACATTCACTCTGGCTGGAGTGTTCAACAACGCGGCAATGACGAGATCGTGATTCTGGTCTCAAGCCTCTA
TCGCGTTGAAGAGCTTGGCCTACCGTTTGTCTTCACAAACGCTCATGCCTACCCGAGTTGGACAAACTACTACAGCGATC
TGGCGAATCTCGACCAGATCGATTGGTCTATCCTTCAACGGCGCGACTTCAAGCGCGATCCTGACGACCCTCGCAAAATG
GAGCGTTATCAGGCTGAGGCGCTGATCCACCAACATTTACCGATTACGGGACTACTGGGCATCATGTGCCACACCGATGC
AATGAAAGTACGCATAGAAGCAGACGTGGCCGTTAGAGGCTTGACGTTGCCGGTCCATGCGCGTCCCAAATGGTATTTCC
AATGA

Antitoxin


Download         Length: 362 a.a.        Molecular weight: 40668.82 Da        Isoelectric Point: 6.5078

>AT120811 WP_134787420.1 NZ_CP038207:6008106-6009191 [Pseudomonas sp. S150]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFAQNYRLYAAACKAGDVETGKMHVTATNELDGPRWIVNFPTK
RHWRYPSQMAWITEGLHDLRRFLLENDVKSVAVPPLGAGNGGLKWPEVREQIVEVLGDLDVDVLVFEPSSQYLNVAKRDG
VEQLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKIPGTENPLNLKFVAHKFGPYANRLEHLLNNLDGSYLH
CDKRISDAGITDVIWFDQDRKTFLQTYLKTEAKEYSQALERTAELIDGFESPFGMELLATVDWLLIRERIAPTVPAVRKA
LMNWDGGSGAAVRKNKLFDDQALGIAITRLTSTSFSPEMAA

Download         Length: 1086 bp

>AT120811 NZ_CP038207:6008106-6009191 [Pseudomonas sp. S150]
ATGATCAGATTCACCCAAGGCAACCTGCTGGAAGCCAAAACTGAAGCGCTCGTCAACACGGTGAATACCGTGGGTGTAAT
GGGTAAGGGCATCGCACTGATGTTCAAGGAACGCTTTGCGCAGAATTACCGACTATATGCAGCCGCGTGCAAAGCCGGGG
ATGTCGAAACCGGCAAAATGCACGTGACTGCCACCAACGAACTCGATGGACCGCGCTGGATTGTGAATTTCCCCACCAAG
CGCCACTGGCGGTACCCGTCGCAAATGGCATGGATAACTGAAGGCTTGCATGATCTGCGACGGTTTCTGCTTGAAAACGA
TGTGAAGTCCGTCGCCGTTCCTCCGCTGGGCGCTGGTAACGGTGGTTTGAAGTGGCCTGAAGTGCGCGAGCAGATTGTAG
AAGTGCTCGGTGACTTGGATGTCGACGTATTAGTGTTCGAACCCTCCAGTCAGTATCTGAATGTCGCTAAGCGCGATGGC
GTTGAGCAACTCACTCCGGCACGCGCACTGATCGCTGAACTGGTCCGGCGTTATTGGGTTCTGGGCATGGAATGCAGCCT
GCTCGAAATTCAGAAACTGGCTTGGTTTCTTGAACGCGCAATCGAGAAAATTCCAGGTACTGAGAATCCGCTGAACCTCA
AATTTGTCGCTCATAAATTCGGCCCGTATGCCAATCGATTGGAGCATCTGCTGAACAATCTGGATGGCAGCTATCTACAT
TGCGACAAGCGCATCAGTGATGCTGGAATCACCGATGTCATTTGGTTTGATCAAGATCGCAAAACGTTTTTGCAGACCTA
CCTCAAGACCGAAGCTAAGGAATACTCTCAAGCTTTAGAGCGGACGGCTGAATTGATCGATGGTTTTGAGTCACCTTTCG
GCATGGAGTTGCTGGCGACCGTTGATTGGTTGCTGATTCGGGAAAGGATTGCTCCAACCGTTCCTGCGGTACGTAAAGCA
CTGATGAACTGGGACGGTGGGTCCGGAGCTGCGGTGCGTAAAAACAAATTATTCGATGATCAGGCACTAGGAATTGCGAT
CACGCGTCTGACATCCACCAGCTTCAGCCCGGAAATGGCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References