Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3367388..3368613 Replicon chromosome
Accession NZ_CP038207
Organism Pseudomonas sp. S150

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag E3Z29_RS15365 Protein ID WP_134786183.1
Coordinates 3367388..3367978 (-) Length 197 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag E3Z29_RS15370 Protein ID WP_134786184.1
Coordinates 3368056..3368613 (-) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3Z29_RS15345 3363955..3364722 - 768 WP_003224391.1 phosphonate ABC transporter, permease protein PhnE -
E3Z29_RS15350 3364719..3365546 - 828 WP_103485021.1 ABC transporter permease subunit -
E3Z29_RS15355 3365540..3366337 - 798 WP_134786181.1 ATP-binding cassette domain-containing protein -
E3Z29_RS15360 3366334..3367197 - 864 WP_134786182.1 putative selenate ABC transporter substrate-binding protein -
E3Z29_RS15365 3367388..3367978 - 591 WP_134786183.1 HD domain-containing protein Toxin
E3Z29_RS15370 3368056..3368613 - 558 WP_134786184.1 helix-turn-helix domain-containing protein Antitoxin
E3Z29_RS15375 3368689..3369087 - 399 WP_134786185.1 RidA family protein -
E3Z29_RS15380 3369210..3370154 + 945 WP_134786186.1 LysR family transcriptional regulator -
E3Z29_RS15385 3370229..3371389 + 1161 WP_134786187.1 radical SAM protein -
E3Z29_RS15390 3371371..3372258 - 888 WP_098968390.1 LysR family transcriptional regulator -
E3Z29_RS15395 3372394..3373446 + 1053 WP_134786188.1 agmatine deiminase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-168)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 197 a.a.        Molecular weight: 21835.58 Da        Isoelectric Point: 4.5028

>T120809 WP_134786183.1 NZ_CP038207:c3367978-3367388 [Pseudomonas sp. S150]
MNLEMIKGRLEFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAIVFADQLAGLDLLKVLKMCVIHDLGEAINGDIP
AVNQAAFPDKGEQERNDLLLLTGALDEALRSEILALWDDYENAQSAEAKAVKALDKLETLLQHNQGLNPADFDYGFNLGY
GKKYTSADPVFATLRELIDQDTQQRISDGQNSNERS

Download         Length: 591 bp

>T120809 NZ_CP038207:c3367978-3367388 [Pseudomonas sp. S150]
ATGAACCTCGAAATGATCAAAGGCCGCCTCGAATTCCTGCGCGAAGCAGAAAAACTCAAGGACGTGCTGCGCAGCGCGCA
CACCTCCAGCGGCCGCACCGAAAGCACCGCCGAACACAGCTGGCGCCTGTGCCTGATGGCGATTGTCTTCGCCGATCAAC
TGGCCGGCCTCGACCTGCTCAAGGTCCTGAAGATGTGCGTGATTCACGATTTGGGCGAAGCCATCAATGGTGACATTCCA
GCGGTCAATCAGGCCGCGTTCCCCGACAAGGGTGAACAGGAACGCAACGACCTTCTGCTGCTGACCGGTGCGCTCGATGA
GGCGCTGCGCAGCGAAATTCTAGCGCTGTGGGACGACTACGAAAATGCTCAGTCCGCCGAAGCCAAAGCGGTCAAGGCAC
TGGATAAACTGGAGACGCTGCTGCAACACAACCAGGGGCTGAACCCGGCGGATTTCGATTACGGTTTCAATCTGGGCTAC
GGCAAGAAATACACCAGTGCCGACCCGGTCTTCGCCACCCTGCGTGAGCTGATCGACCAAGACACGCAACAGCGCATCAG
CGACGGCCAAAACAGCAACGAGCGATCCTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20444.63 Da        Isoelectric Point: 10.6088

>AT120809 WP_134786184.1 NZ_CP038207:c3368613-3368056 [Pseudomonas sp. S150]
MSDLLLKPALPGIALRRWRLLHRVKQTHAAQLFNVTQSTISRWESGVQAMEPAAQLQLERLLTARLDSAADQVLARLIGE
SQRPMHLICDLTHRLLACSPARAAEFTRPLSTLLGQSLWRFATPEIVLRESALATSGWHEVQAPPAVEFSTGSNASDLVP
IRAGRCRWTRIPLSDGSAARLVETL

Download         Length: 558 bp

>AT120809 NZ_CP038207:c3368613-3368056 [Pseudomonas sp. S150]
ATGTCAGACCTGTTATTGAAGCCCGCCCTGCCCGGTATCGCCCTGCGACGCTGGCGCCTGCTGCATCGCGTCAAACAGAC
TCACGCGGCGCAGTTGTTCAACGTCACCCAGTCGACCATTTCCCGCTGGGAAAGCGGTGTGCAGGCGATGGAACCTGCCG
CGCAACTGCAACTGGAGCGTTTGCTGACTGCGCGCCTGGACAGCGCCGCCGATCAGGTCTTGGCGCGTCTGATCGGGGAA
AGTCAGCGGCCGATGCACCTGATCTGCGACCTCACCCATCGCCTGCTGGCCTGCTCTCCTGCGCGTGCTGCCGAGTTCAC
CCGACCCTTGAGTACGTTGCTGGGACAATCGCTGTGGCGCTTCGCAACGCCGGAAATTGTGCTGAGAGAGTCGGCGCTGG
CAACCAGCGGTTGGCACGAAGTTCAGGCGCCGCCAGCCGTGGAATTCAGCACCGGCAGCAATGCCTCCGACCTCGTGCCG
ATCCGCGCCGGCCGATGCCGCTGGACGCGCATTCCACTCTCCGACGGCAGCGCCGCGCGGCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References